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Novel membrane-based biotechnological alternative process for succinic acid production and chemical synthesis of bio-based poly (butylene succinate)
Alternative TitleBioresour. Technol.
Wang, Caixia1,2; Ming, Wei3; Yan, Daojiang1,2; Zhang, Congcong3; Yang, Maohua1; Liu, Yilan1,2; Zhang, Yu4; Guo, Baohua4; Wan, Yinhua1; Xing, Jianmin1
2014-03-01
Source PublicationBIORESOURCE TECHNOLOGY
ISSN0960-8524
Volume156Issue:1Pages:6-13
AbstractSuccinic acid was produced in a novel membrane-based fermentation and separation integrated system. With this integrated system, product inhibition was alleviated by removing acids and replenishing fresh broth. High cell density maintain for a longer time from 75 to 130 h and succinic acid concentration increased from 53 to 73 g/L. In the developed separation process, succinic acid was crystallized at a recovery of 85-90%. The purity of the obtained succinic acid crystals reached 99.4% as found by HPLC and H-1 NMR analysis. A crystallization experiment indicated that among by-products glucose had a negative effect on succinic acid crystallization. Poly (butylene succinate) (PBS) was synthesized using the purified succinic acid and H-1 NMR analysis confirmed that the composition of the synthesized PBS is in agreement with that from petro-based succinic acid. Crown Copyright (C) 2013 Published by Elsevier Ltd. All rights reserved.; Succinic acid was produced in a novel membrane-based fermentation and separation integrated system. With this integrated system, product inhibition was alleviated by removing acids and replenishing fresh broth. High cell density maintain for a longer time from 75 to 130 h and succinic acid concentration increased from 53 to 73 g/L. In the developed separation process, succinic acid was crystallized at a recovery of 85-90%. The purity of the obtained succinic acid crystals reached 99.4% as found by HPLC and H-1 NMR analysis. A crystallization experiment indicated that among by-products glucose had a negative effect on succinic acid crystallization. Poly (butylene succinate) (PBS) was synthesized using the purified succinic acid and H-1 NMR analysis confirmed that the composition of the synthesized PBS is in agreement with that from petro-based succinic acid. Crown Copyright (C) 2013 Published by Elsevier Ltd. All rights reserved.
KeywordSuccinic Acid Membrane Separation Integrated Process Poly (Butylene Succinate) Synthesis
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Technology
DOI10.1016/j.biortech.2013.12.043
URL查看原文
Indexed BySCI
Language英语
WOS KeywordESCHERICHIA-COLI ; FERMENTATION ; YIELD ; TRANSFORMATIONS ; ESTERIFICATION ; DESIGN
WOS Research AreaAgriculture ; Biotechnology & Applied Microbiology ; Energy & Fuels
WOS SubjectAgricultural Engineering ; Biotechnology & Applied Microbiology ; Energy & Fuels
WOS IDWOS:000334828500002
Citation statistics
Cited Times:22[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/10969
Collection研究所(批量导入)
Affiliation1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Grad Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Beijing Forestry Univ, Dept Biol Sci & Technol, Beijing 100083, Peoples R China
4.Tsinghua Univ, Inst Polymer Sci & Engn, Dept Chem Engn, Beijing 100084, Peoples R China
Recommended Citation
GB/T 7714
Wang, Caixia,Ming, Wei,Yan, Daojiang,et al. Novel membrane-based biotechnological alternative process for succinic acid production and chemical synthesis of bio-based poly (butylene succinate)[J]. BIORESOURCE TECHNOLOGY,2014,156(1):6-13.
APA Wang, Caixia.,Ming, Wei.,Yan, Daojiang.,Zhang, Congcong.,Yang, Maohua.,...&Xing, Jianmin.(2014).Novel membrane-based biotechnological alternative process for succinic acid production and chemical synthesis of bio-based poly (butylene succinate).BIORESOURCE TECHNOLOGY,156(1),6-13.
MLA Wang, Caixia,et al."Novel membrane-based biotechnological alternative process for succinic acid production and chemical synthesis of bio-based poly (butylene succinate)".BIORESOURCE TECHNOLOGY 156.1(2014):6-13.
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