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Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15
Alternative TitleJ. Appl. Microbiol.
Wang, L.1; He, H.1; Zhang, C.1; Sun, L.1; Liu, S.1; Yue, R.2
2014-05-01
Source PublicationJOURNAL OF APPLIED MICROBIOLOGY
ISSN1364-5072
Volume116Issue:5Pages:1106-1118
AbstractAims To synthesize silver-loaded mesoporous silica SBA-15 (Ag/SBA-15) materials and examine their antimicrobial action and antimicrobial mechanism. Methods and Results Ag/SBA-15 materials were prepared by means of incipient wetness impregnation, impregnation and direct hydrothermal synthesis methods. The antimicrobial activity of Ag/SBA-15 was investigated using Escherichia coli as an indicator bacterium, and the antimicrobial mechanism was explored. The properties and Ag+ release behaviour of Ag/SBA-15 materials were compared. Experimental results showed that Ag/SBA-15 materials resulted in 7 center dot 5 log inactivation of E.coli for only 60min, which exhibited very high antimicrobial activities at room temperature without using any light or electrical power input. The cell wall and cell membrane were destroyed in the antimicrobial process, leading to leakage of intracellular components. The formation of extracellular reactive oxygen species (ROS) involved in the bactericidal process was confirmed. Production of intracellular ROS was also discovered. Conclusions Ag/SBA-15 exhibited high antimicrobial activity against E.coli. This antimicrobial effect was a synergistic action between extracellular ROS and the toxicity of Ag+, which induced intracellular ROS production and subsequent cell death. Significance and Impact of the Study This study revealed for the first time the antimicrobial activities and mechanisms of Ag/SBA-15 materials prepared with different methods.; Aims To synthesize silver-loaded mesoporous silica SBA-15 (Ag/SBA-15) materials and examine their antimicrobial action and antimicrobial mechanism. Methods and Results Ag/SBA-15 materials were prepared by means of incipient wetness impregnation, impregnation and direct hydrothermal synthesis methods. The antimicrobial activity of Ag/SBA-15 was investigated using Escherichia coli as an indicator bacterium, and the antimicrobial mechanism was explored. The properties and Ag+ release behaviour of Ag/SBA-15 materials were compared. Experimental results showed that Ag/SBA-15 materials resulted in 7 center dot 5 log inactivation of E.coli for only 60min, which exhibited very high antimicrobial activities at room temperature without using any light or electrical power input. The cell wall and cell membrane were destroyed in the antimicrobial process, leading to leakage of intracellular components. The formation of extracellular reactive oxygen species (ROS) involved in the bactericidal process was confirmed. Production of intracellular ROS was also discovered. Conclusions Ag/SBA-15 exhibited high antimicrobial activity against E.coli. This antimicrobial effect was a synergistic action between extracellular ROS and the toxicity of Ag+, which induced intracellular ROS production and subsequent cell death. Significance and Impact of the Study This study revealed for the first time the antimicrobial activities and mechanisms of Ag/SBA-15 materials prepared with different methods.
KeywordE.coli Reactive Oxygen Species Antimicrobial Activity Sba-15 Silver
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1111/jam.12443
URL查看原文
Indexed BySCI
Language英语
WOS KeywordESCHERICHIA-COLI ; BACTERICIDAL ACTIVITY ; NO REDUCTION ; NANOPARTICLES ; ZEOLITE ; OXIDATION ; CATALYSTS ; SURFACE ; DISINFECTION ; MICROSCOPY
WOS Research AreaBiotechnology & Applied Microbiology ; Microbiology
WOS SubjectBiotechnology & Applied Microbiology ; Microbiology
WOS IDWOS:000334062400004
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Cited Times:15[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/10975
Collection研究所(批量导入)
Affiliation1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, Beijing 100085, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, Beijing 100085, Peoples R China
Recommended Citation
GB/T 7714
Wang, L.,He, H.,Zhang, C.,et al. Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15[J]. JOURNAL OF APPLIED MICROBIOLOGY,2014,116(5):1106-1118.
APA Wang, L.,He, H.,Zhang, C.,Sun, L.,Liu, S.,&Yue, R..(2014).Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15.JOURNAL OF APPLIED MICROBIOLOGY,116(5),1106-1118.
MLA Wang, L.,et al."Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15".JOURNAL OF APPLIED MICROBIOLOGY 116.5(2014):1106-1118.
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