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Biosafe Nanoscale Pharmaceutical Adjuvant Materials
Alternative TitleJ. Biomed. Nanotechnol.
Jin, Shubin1; Li, Shengliang1,2; Wang, Chongxi1; Liu, Juan1; Yang, Xiaolong1; Wang, Paul C.3; Zhang, Xin4; Liang, Xing-Jie1
2014-09-01
Source PublicationJOURNAL OF BIOMEDICAL NANOTECHNOLOGY
ISSN1550-7033
Volume10Issue:9Pages:2393-2419
AbstractThanks to developments in the field of nanotechnology over the past decades, more and more biosafe nanoscale materials have become available for use as pharmaceutical adjuvants in medical research. Nanomaterials possess unique properties which could be employed to develop drug carriers with longer circulation time, higher loading capacity, better stability in physiological conditions, controlled drug release, and targeted drug delivery. In this review article, we will review recent progress in the application of representative organic, inorganic and hybrid biosafe nanoscale materials in pharmaceutical research, especially focusing on nanomaterial-based novel drug delivery systems. In addition, we briefly discuss the advantages and notable functions that make these nanomaterials suitable for the design of new medicines; the biosafety of each material discussed in this article is also highlighted to provide a comprehensive understanding of their adjuvant attributes.; Thanks to developments in the field of nanotechnology over the past decades, more and more biosafe nanoscale materials have become available for use as pharmaceutical adjuvants in medical research. Nanomaterials possess unique properties which could be employed to develop drug carriers with longer circulation time, higher loading capacity, better stability in physiological conditions, controlled drug release, and targeted drug delivery. In this review article, we will review recent progress in the application of representative organic, inorganic and hybrid biosafe nanoscale materials in pharmaceutical research, especially focusing on nanomaterial-based novel drug delivery systems. In addition, we briefly discuss the advantages and notable functions that make these nanomaterials suitable for the design of new medicines; the biosafety of each material discussed in this article is also highlighted to provide a comprehensive understanding of their adjuvant attributes.
KeywordDrug Delivery Adjuvant Nanomaterials Biosafe Multifunction Nanoparticle Controlled Release
SubtypeReview
WOS HeadingsScience & Technology ; Technology
DOI10.1166/jbn.2014.1898
URL查看原文
Indexed BySCI
Language英语
WOS KeywordMESOPOROUS SILICA NANOPARTICLES ; TARGETED DRUG-DELIVERY ; GLYCOL CHITOSAN NANOPARTICLES ; RESPONSIVE CONTROLLED-RELEASE ; SIZE-DEPENDENT CYTOTOXICITY ; CELL-PENETRATING PEPTIDES ; CORE-SHELL NANOPARTICLES ; IRON-OXIDE NANOPARTICLES ; WATER-SOLUBLE CHITOSAN ; GROWTH-FACTOR RECEPTOR
WOS Research AreaScience & Technology - Other Topics ; Materials Science
WOS SubjectNanoscience & Nanotechnology ; Materials Science, Biomaterials
WOS IDWOS:000339430600031
Citation statistics
Cited Times:22[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/11334
Collection研究所(批量导入)
Affiliation1.Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
2.Sun Yat Sen Univ, Zhongshan Sch Med, Dept Neurobiol & Anat, Guangzhou 510275, Guangdong, Peoples R China
3.Howard Univ, Dept Radiol, Lab Mol Imaging, Washington, DC 20060 USA
4.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Jin, Shubin,Li, Shengliang,Wang, Chongxi,et al. Biosafe Nanoscale Pharmaceutical Adjuvant Materials[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2014,10(9):2393-2419.
APA Jin, Shubin.,Li, Shengliang.,Wang, Chongxi.,Liu, Juan.,Yang, Xiaolong.,...&Liang, Xing-Jie.(2014).Biosafe Nanoscale Pharmaceutical Adjuvant Materials.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,10(9),2393-2419.
MLA Jin, Shubin,et al."Biosafe Nanoscale Pharmaceutical Adjuvant Materials".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 10.9(2014):2393-2419.
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