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Clarification of succinic acid fermentation broth by ultrafiltration in succinic acid biorefinery
Wang, Caixia1,2; Li, Qiang1; Tang, Huang1,2; Zhou, Wei1,2; Yan, Daojiang1,2; Xing, Jianmin1; Wan, Yinhua1
2013-03-01
Source PublicationJOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
Volume88Issue:3Pages:444-448
AbstractBACKGROUND: Succinic acid is an important precursor chemical for the synthesis of high value-added products. In this work, ultrafiltration was first investigated to clarify succinic acid fermentation broth by integrating fermentation and separation and removal processes of the product in situ. Four different ultrafiltration membranes (PES 100 kDa, PES 30 kDa, PES 10 kDa and RC 10 kDa) were used in this work. RESULTS: Results indicate that ultrafiltration is feasible for clarifying succinic acid fermentation broth. Almost all the microorganism cells (99.6%) were removed from the fermentation broth. Proteins were also removed effectively by all the membranes studied. The removal rate was 79.86% for PES 100 kDa, 86.43% for PES 30 kDa, 86.83% for PES 10 kDa, and 80.06% for the RC 10 kDa. After ultrafiltration, a clearer permeate was obtained compared with that from centrifugation. CONCLUSION: Membranes operating at high flux are always susceptible to rapid fouling. Compared with molecular weight cut-offs (MWCO), membrane material has a significant influence on the flux. Membrane flux measured in this study shows industrial potential of this technology in treatment of succinic acid fermentation broth. (c) 2012 Society of Chemical Industry
KeywordClarification Succinic Acid Fermentation Broth Separation Ultrafiltration
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
Indexed BySCI
Language英语
WOS KeywordLACTIC-ACID ; SEPARATION ; MEMBRANES ; PROTEIN ; FILTRATION ; REJECTION ; SURFACTIN ; RECOVERY ; FLUX
WOS Research AreaBiotechnology & Applied Microbiology ; Chemistry ; Engineering
WOS SubjectBiotechnology & Applied Microbiology ; Chemistry, Multidisciplinary ; Engineering, Chemical
WOS IDWOS:000315123400015
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Cited Times:16[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/13426
Collection研究所(批量导入)
Affiliation1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Wang, Caixia,Li, Qiang,Tang, Huang,et al. Clarification of succinic acid fermentation broth by ultrafiltration in succinic acid biorefinery[J]. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,2013,88(3):444-448.
APA Wang, Caixia.,Li, Qiang.,Tang, Huang.,Zhou, Wei.,Yan, Daojiang.,...&Wan, Yinhua.(2013).Clarification of succinic acid fermentation broth by ultrafiltration in succinic acid biorefinery.JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,88(3),444-448.
MLA Wang, Caixia,et al."Clarification of succinic acid fermentation broth by ultrafiltration in succinic acid biorefinery".JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 88.3(2013):444-448.
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