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Pilot-Scale Gas Double-Dynamic Solid-State Fermentation for the Production of Industrial Enzymes
He, Qin; Chen, Hongzhang
2013-10-01
Source PublicationFOOD AND BIOPROCESS TECHNOLOGY
Volume6Issue:10Pages:2916-2924
AbstractPresently, the modern solid-state fermentation (SSF) industry remains traditional; there are few designs available for bioreactors operating in SSF on a large scale, which is mainly caused by the problems in engineering that appear when scaling up this technique. Gas double-dynamic solid-state fermentation (GDD-SSF) technology has been proven available in industrial production of biopesticide. However, there are few other examples using the GDD-SSF technology in other fermentation industries. To test its applicability in other fermentation industries, the self-made pilot-scale bioreactor for GDD-SSF of 800 L was used for the production of various typical enzymes. The comparing effects of liquid-solid ratio and air pressure on enzyme production in different fermentation modes were investigated. Results showed that GDD-SSF offered greater advantages to the static SSF in industrial enzyme preparation, such as pectinase, glucoamylase, protease, and cellulase. It could not only improve enzyme activities with a largest increase reached 2.84 times but also shorten the fermentation period. Furthermore, decreased temperature gradient was found in GDD-SSF, which is crucial for online controlling in industry production. Thus, the necessary and successful pilot-scale fermentation of various enzymes was a rational indication of applicability to large-scale SSF by GDD-SSF.
KeywordIndustrial Enzymes Enzyme Activity Gas Double-dynamic Solid-state Fermentation (Gdd-ssf) Pilot Scale Solid-state Fermentation
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Indexed BySCI
Language英语
WOS KeywordAIR-PRESSURE PULSATION ; ASPERGILLUS-NIGER ; CELLULASE PRODUCTION ; WATER ACTIVITY ; BIOREACTOR ; PROTEASE ; CULTURE ; REACTOR ; DESIGN ; STRAW
WOS Research AreaFood Science & Technology
WOS SubjectFood Science & Technology
WOS IDWOS:000323881800032
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/13430
Collection研究所(批量导入)
AffiliationChinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
He, Qin,Chen, Hongzhang. Pilot-Scale Gas Double-Dynamic Solid-State Fermentation for the Production of Industrial Enzymes[J]. FOOD AND BIOPROCESS TECHNOLOGY,2013,6(10):2916-2924.
APA He, Qin,&Chen, Hongzhang.(2013).Pilot-Scale Gas Double-Dynamic Solid-State Fermentation for the Production of Industrial Enzymes.FOOD AND BIOPROCESS TECHNOLOGY,6(10),2916-2924.
MLA He, Qin,et al."Pilot-Scale Gas Double-Dynamic Solid-State Fermentation for the Production of Industrial Enzymes".FOOD AND BIOPROCESS TECHNOLOGY 6.10(2013):2916-2924.
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