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A novel structured bioreactor for solid-state fermentation
Chen, Hongzhang1; He, Qin1,2
2013-02-01
Source PublicationBIOPROCESS AND BIOSYSTEMS ENGINEERING
Volume36Issue:2Pages:223-230
AbstractA novel patented solid-state bioreactor (251 L) with honeycomb loading device was designed and its performance was tested. First, this apparatus gave a 66.87 % of calculated loading coefficient (volume ratio), which was almost twofold compared with conventional fermenters. Next, considering the crucial effect of heat transfer on bed loading and microbial growth, the performance was validated by temperature variance during fermentation and spore viability of Bacillus cereus DM423. Air pressure pulsation or external water jacket was used to control temperature; the maximal temperature variation was 7.7 versus 19.8 A degrees C, respectively during fermentation. The difference was mainly due to the continuous gas phase characterized by solid-state fermentation (SSF). The average living spores of (1.50 +/- A 0.07) x 10(11) cfu/g at 40 h obtained from the device was higher than (0.70 +/- A 0.03) x 10(11) cfu/g from flask at 48 h. The results indicated that this new loading bioreactor with air pressure pulsation could be a good prospect for industrialization of SSF employing bacterial cultures.
KeywordHoneycomb Loading Device Loading Coefficient Air Pressure Pulsation Solid-state Fermentation Temperature Control
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Technology
Indexed BySCI
Language英语
WOS KeywordTRANSPORT RESISTANCES ; BIOCHEMICAL REACTION ; ASPERGILLUS-NIGER ; DYNAMIC CHANGES ; AIR ; REACTOR ; TEMPERATURE ; FERMENTERS ; GRADIENTS ; DESIGN
WOS Research AreaBiotechnology & Applied Microbiology ; Engineering
WOS SubjectBiotechnology & Applied Microbiology ; Engineering, Chemical
WOS IDWOS:000314269900010
Citation statistics
Cited Times:14[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/13443
Collection研究所(批量导入)
Affiliation1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Chen, Hongzhang,He, Qin. A novel structured bioreactor for solid-state fermentation[J]. BIOPROCESS AND BIOSYSTEMS ENGINEERING,2013,36(2):223-230.
APA Chen, Hongzhang,&He, Qin.(2013).A novel structured bioreactor for solid-state fermentation.BIOPROCESS AND BIOSYSTEMS ENGINEERING,36(2),223-230.
MLA Chen, Hongzhang,et al."A novel structured bioreactor for solid-state fermentation".BIOPROCESS AND BIOSYSTEMS ENGINEERING 36.2(2013):223-230.
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