CAS OpenIR  > 生化工程国家重点实验室
Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy
Zhang, Weifeng1,2; Wang, Lianyan1; Yang, Tingyuan1; Liu, Yuan1,2; Chen, Xiaoming1,2; Liu, Qi1,2; Jia, Jilei1,2; Ma, Guanghui1,3
2015-09-01
Source PublicationPHARMACEUTICAL RESEARCH
ISSN0724-8741
Volume32Issue:9Pages:2837-2850
Abstract

Adjuvants are required to ensure the efficacy of subunit vaccines. Incorporating molecular immunopotentiators within particles could overcome drawbacks of molecular adjuvants (such as solubility and toxicity), and improve adjuvanticity of particles, achieving stronger adjuvant activity. Aim of this study is to evaluate the adjuvanticity of immunopotentiator-loaded polymeric particles for subunit vaccine.

KeywordAdjuvant Imiquimod Immune Response Microparticles Subunit Vaccine
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences ; Life Sciences & Biomedicine
DOI10.1007/s11095-015-1666-6
Indexed BySCI
Language英语
WOS KeywordIMMUNE-RESPONSES ; ACETALATED DEXTRAN ; CELL-ACTIVATION ; ANTIGEN ; NANOPARTICLES ; DELIVERY ; IMIQUIMOD ; CD69
WOS Research AreaChemistry ; Pharmacology & Pharmacy
WOS SubjectChemistry, Multidisciplinary ; Pharmacology & Pharmacy
WOS IDWOS:000359140800004
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/19427
Collection生化工程国家重点实验室
Affiliation1.Chinese Acad Sci, Natl Key Lab Biochem Engn, PLA Key Lab Biopharmaceut Prod & Formulat Engn, Inst Proc Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Weifeng,Wang, Lianyan,Yang, Tingyuan,et al. Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy[J]. PHARMACEUTICAL RESEARCH,2015,32(9):2837-2850.
APA Zhang, Weifeng.,Wang, Lianyan.,Yang, Tingyuan.,Liu, Yuan.,Chen, Xiaoming.,...&Ma, Guanghui.(2015).Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy.PHARMACEUTICAL RESEARCH,32(9),2837-2850.
MLA Zhang, Weifeng,et al."Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy".PHARMACEUTICAL RESEARCH 32.9(2015):2837-2850.
Files in This Item:
File Name/Size DocType Version Access License
Immunopotentiator-Lo(6174KB)期刊论文出版稿限制开放CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhang, Weifeng]'s Articles
[Wang, Lianyan]'s Articles
[Yang, Tingyuan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhang, Weifeng]'s Articles
[Wang, Lianyan]'s Articles
[Yang, Tingyuan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhang, Weifeng]'s Articles
[Wang, Lianyan]'s Articles
[Yang, Tingyuan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.