CAS OpenIR  > 研究所(批量导入)
Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications
Parvin, Nargish1,3; Mandal, Tapas K.2,3
2016
发表期刊RSC ADVANCES
ISSN2046-2069
卷号6期号:22页码:18134-18140
摘要

Highly fluorescent, broad range pH and ionic-stable N-doped carbon quantum dots (N-CQDs) were successfully synthesized and their chemical structure and fluorescence mechanism were characterized. Mono-dispersed N-CQDs averaging 4.5 nm in diameter were achieved in a quantum yield (QY) of 74.16%. These N-CQDs showed great potential in biomedical and optical imaging applications both in vivo and in vitro. Biodistribution, retention, toxicity, and pharmacokinetics profiles are mandatory in their potential clinical applications. Herein, the biodistribution, clearance, and toxicity of our invariable N-CQDs species were systematically investigated over 7 days in mice. Most of the N-CQDs were cleared at 6 days post-injection without any accumulation in any vital organs or tissues. Moreover, the high fluorescence N-CQDs were demonstrated to be effective as printing inks for multicolour patterns. This study suggests that N-CQDs may be an attractive alternative to metal quantum dots for secure biomedical and other industrial applications.

关键词Coated Gold Nanoparticles Sensitive Detection Facile Synthesis Renal Clearance Graphene Oxide Nanodots Toxicity Ions Size Biodistribution
文章类型Article
学科领域Chemistry, Multidisciplinary ; Chemistry
WOS标题词Science & Technology ; Physical Sciences
DOI10.1039/c5ra25402g
URL查看原文
收录类别SCI
语种英语
关键词[WOS]Coated Gold Nanoparticles ; Sensitive Detection ; Facile Synthesis ; Renal Clearance ; Graphene Oxide ; Nanodots ; Toxicity ; Ions ; Size ; Biodistribution
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
项目资助者SERB ; DST(SR/FT/LS-76/2012) ; DBT Government of India ; Chinese Academy of Science postdoctoral and visiting scholar for developing country programme
WOS记录号WOS:000370717900040
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ipe.ac.cn/handle/122111/20708
专题研究所(批量导入)
通讯作者Mandal, Tapas K.
作者单位1.Chinese Acad Sci, Inst Proc Engn, Key Lab Biochem Engn, 1 Bei Erjie, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Inst Chem, Bei Yi Jie 2, Beijing 100190, Peoples R China
3.Indian Inst Technol, Dept Biotechnol, Roorkee 247667, Uttar Pradesh, India
推荐引用方式
GB/T 7714
Parvin, Nargish,Mandal, Tapas K.. Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications[J]. RSC ADVANCES,2016,6(22):18134-18140.
APA Parvin, Nargish,&Mandal, Tapas K..(2016).Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications.RSC ADVANCES,6(22),18134-18140.
MLA Parvin, Nargish,et al."Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications".RSC ADVANCES 6.22(2016):18134-18140.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Synthesis of a highl(826KB)期刊论文出版稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Parvin, Nargish]的文章
[Mandal, Tapas K.]的文章
百度学术
百度学术中相似的文章
[Parvin, Nargish]的文章
[Mandal, Tapas K.]的文章
必应学术
必应学术中相似的文章
[Parvin, Nargish]的文章
[Mandal, Tapas K.]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Synthesis of a highly fluorescence nitrogen-doped carbon quantum dots bioimaging probe and its in vivo clearance and printing applications.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。