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Preparation of Uniform-Sized and Dual Stimuli-Responsive Microspheres of Poly(N-Isopropylacrylamide)/Poly(Acrylic acid) with Semi-IPN Structure by One-Step Method
Lai, En-Ping1,2; Wang, Yu-Xia2; Wei, Yi2; Li, Guang1
2016-03-01
Source PublicationPOLYMERS
ISSN2073-4360
Volume8Issue:3Pages:1
AbstractA novel strategy was developed to synthesize uniform semi-interpenetrating polymer network (semi-IPN) microspheres by premix membrane emulsification combined with one-step polymerization. Synthesized poly(acrylic acid) (PAAc) polymer chains were added prior to the inner water phase, which contained N-isopropylacrylamide (NIPAM) monomer, N,N '-methylene bisacrylamide (MBA) cross-linker, and ammonium persulfate (APS) initiator. The mixtures were pressed through a microporous membrane to form a uniform water-in-oil emulsion. By crosslinking the NIPAM in a PAAc-containing solution, microspheres with temperature- and pH-responsive properties were fabricated. The semi-IPN structure and morphology of the microspheres were confirmed by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The average diameter of the obtained microspheres was approximately 6.5 mu m, with Span values of less than 1. Stimuli-responsive behaviors of the microspheres were studied by the cloud-point method. The results demonstrated that semi-IPN microspheres could respond independently to both pH and temperature changes. After storing in a PBS solution (pH 7.0) at 4 degrees C for 6 months, the semi-IPN microspheres remained stable without a change in morphology or particle size. This study demonstrated a promising method for controlling the synthesis of semi-IPN structure microspheres with a uniform size and multiple functionalities.
KeywordUniform Microspheres Premix Membrane Emulsification Semi-interpenetrating Polymer Network (Semi-ipn) Poly(N-isopropylacrylamide) (Pnipam) Stimuli-responsive
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
DOI10.3390/polym8030090
Indexed BySCI
Language英语
WOS KeywordINTERPENETRATING POLYMER NETWORKS ; MICROGEL PARTICLES ; ACRYLIC-ACID ; HYDROGELS ; TEMPERATURE ; RELEASE ; MICROCAPSULES ; ACRYLAMIDE ; BEHAVIOR ; PH
WOS Research AreaPolymer Science
WOS SubjectPolymer Science
Funding OrganizationBeijing Municipal Science and Technology Commission(Z141100000214007) ; National Natural Science Foundation of China(51173187 ; 21336010)
WOS IDWOS:000373711700006
Citation statistics
Cited Times:16[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/21003
Collection生化工程国家重点实验室
Affiliation1.Donghua Univ, Coll Mat Sci & Engn, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Lai, En-Ping,Wang, Yu-Xia,Wei, Yi,et al. Preparation of Uniform-Sized and Dual Stimuli-Responsive Microspheres of Poly(N-Isopropylacrylamide)/Poly(Acrylic acid) with Semi-IPN Structure by One-Step Method[J]. POLYMERS,2016,8(3):1.
APA Lai, En-Ping,Wang, Yu-Xia,Wei, Yi,&Li, Guang.(2016).Preparation of Uniform-Sized and Dual Stimuli-Responsive Microspheres of Poly(N-Isopropylacrylamide)/Poly(Acrylic acid) with Semi-IPN Structure by One-Step Method.POLYMERS,8(3),1.
MLA Lai, En-Ping,et al."Preparation of Uniform-Sized and Dual Stimuli-Responsive Microspheres of Poly(N-Isopropylacrylamide)/Poly(Acrylic acid) with Semi-IPN Structure by One-Step Method".POLYMERS 8.3(2016):1.
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