CAS OpenIR  > 湿法冶金清洁生产技术国家工程实验室
Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery
Du, Xin1,5; Li, Xiaoyu2; Xiong, Lin5; Zhang, Xueji1; Kleitz, Freddy3,4; Qiao, Shi Zhang5
2016-06-01
Source PublicationBIOMATERIALS
ISSN0142-9612
Volume91Issue:JUNEPages:90-127
AbstractMesoporous silica material with organo-bridged silsesquioxane frameworks is a kind of synergistic combination of inorganic silica, mesopores and organics, resulting in some novel or enhanced physicochemical and biocompatible properties compared with conventional mesoporous silica materials with pure Si-O composition. With the rapid development of nanotechnology, monodispersed nanoscale periodic mesoporous organosilica nanoparticles (PMO NPs) and organo-bridged mesoporous silica nano particles (MSNs) with various organic groups and structures have recently been synthesized from 100%, or less, bridged organosilica precursors, respectively. Since then, these materials have been employed as carrier platforms to construct bioimaging and/or therapeutic agent delivery nanosystems for nano biomedical application, and they demonstrate some unique and/or enhanced properties and performances. This review article provides a comprehensive overview of the controlled synthesis of PMO NPs and organ-bridged MSNs, physicochemical and biocompatible properties, and their nano-biomedical application as bioimaging agent and/or therapeutic agent delivery system. (c) 2016 Elsevier Ltd. All rights reserved.
KeywordPmos Mesoporous Nanoparticles Biocompatible Properties Advanced Nanocarriers Bioimaging Therapeutic Agent Delivery
SubtypeReview
WOS HeadingsScience & Technology ; Technology
DOI10.1016/j.biomaterials.2016.03.019
Indexed BySCI
Language英语
WOS KeywordINORGANIC HYBRID MATERIALS ; DRUG-DELIVERY ; GENE DELIVERY ; HOLLOW SPHERES ; CANCER-CELLS ; BIOMEDICAL APPLICATIONS ; FLUORESCENT HYBRID ; PORE WALLS ; TOPOLOGICAL TRANSFORMATION ; SURFACE FUNCTIONALIZATION
WOS Research AreaEngineering ; Materials Science
WOS SubjectEngineering, Biomedical ; Materials Science, Biomaterials
Funding OrganizationNational Natural Science Foundation of China(21501009 ; High-Level Talent Introduction Plan of University of Science & Technology Beijing(06500017) ; Fundamental Research Funds for the Central Universities(FRF-TP-15-019A1) ; Australian Research Council (ARC)(DP130104459 ; Natural Sciences and Engineering Research Council of Canada (NSERC) ; 21127007) ; DP140104062)
WOS IDWOS:000374611900008
Citation statistics
Cited Times:105[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/21015
Collection湿法冶金清洁生产技术国家工程实验室
Affiliation1.Univ Sci & Technol Beijing, Res Ctr Bioengn & Sensing Technol, Beijing 100083, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China
3.Univ Laval, Dept Chem, Quebec City, PQ G1V 0A6, Canada
4.Univ Laval, Ctr Rech Mat Avances CERMA, Quebec City, PQ G1V 0A6, Canada
5.Univ Adelaide, Sch Chem Engn, Adelaide, SA 5005, Australia
Recommended Citation
GB/T 7714
Du, Xin,Li, Xiaoyu,Xiong, Lin,et al. Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery[J]. BIOMATERIALS,2016,91(JUNE):90-127.
APA Du, Xin,Li, Xiaoyu,Xiong, Lin,Zhang, Xueji,Kleitz, Freddy,&Qiao, Shi Zhang.(2016).Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery.BIOMATERIALS,91(JUNE),90-127.
MLA Du, Xin,et al."Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery".BIOMATERIALS 91.JUNE(2016):90-127.
Files in This Item:
File Name/Size DocType Version Access License
Mesoporous silica na(16077KB)期刊论文出版稿限制开放CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Du, Xin]'s Articles
[Li, Xiaoyu]'s Articles
[Xiong, Lin]'s Articles
Baidu academic
Similar articles in Baidu academic
[Du, Xin]'s Articles
[Li, Xiaoyu]'s Articles
[Xiong, Lin]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Du, Xin]'s Articles
[Li, Xiaoyu]'s Articles
[Xiong, Lin]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.