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Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique
Zhang, Bo1,2; Yang, Tingyuan1; Wang, Qibao2; Zhang, Guifeng1; Huo, Junsheng3; Huang, Jian3; Wang, Lianyan1
2016-06-05
发表期刊COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
ISSN0927-7757
卷号498期号:JUNE页码:128-138
摘要In this study, the uniform alginate-agarose microcapsules entrapping FeSO4 were successfully fabricated by premix membrane emulsification technique combined with ionic crosslinking solidification method. It was the first time to employ four phase emulsions system of W-1/O-1/W-2/O-2 for encapsulating FeSO4 into alginate-agarose microcapsules. We systematically investigated how the preparation parameters including type of oil phase and emulsifier, concentrations of alginate and agarose and volume ratios between oil and water phase influenced the stability of emulsions, the morphology and size distributions of microcapsules and loading efficiency of FeSO4. We found that the stability of emulsion was improved with the increase of viscosity and density of outer oil phase (O-2), the concentration of emulsifier as well as the volume ratio between inner water phase and inner oil phase (W-1/O-1) within a certain range. Besides, loading capacity of Fe2+ in alginate/agarose microcapsules presented an increase tendency with the decrease of the volume ratio between external water phase (W-2) and primary emulsion [W-2/(O-1/W-1) (v/v)], and also decreased with the concentration of W-2.
关键词Premix Membrane Emulsification Water-oil-water-oil Multiple Emulsion System Alginate Agarose Microcapsules Feso4 Encapsulation
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
DOI10.1016/j.colsurfa.2016.03.039
收录类别SCI
语种英语
关键词[WOS]INVERSION TEMPERATURE METHOD ; ATOMIC-FORCE MICROSCOPY ; IRON-DEFICIENCY ANEMIA ; W/O NANO-EMULSIONS ; MECHANICAL-PROPERTIES ; FERROUS SULFATE ; MICROSPHERES ; PARTICLES ; MICROPARTICLES ; ENCAPSULATION
WOS研究方向Chemistry
WOS类目Chemistry, Physical
项目资助者Ministry of Science and Technology of the People's Republic of China(2013EG150138)
WOS记录号WOS:000375165700016
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ipe.ac.cn/handle/122111/21038
专题生化工程国家重点实验室
作者单位1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.China Univ Ming & Technol, Sch Chem & Environm Engn, Beijing 100083, Peoples R China
3.Chinese Ctr Dis Control & Prevent, Natl Inst Nutr & Hlth, Beijing 100050, Peoples R China
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Zhang, Bo,Yang, Tingyuan,Wang, Qibao,et al. Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2016,498(JUNE):128-138.
APA Zhang, Bo.,Yang, Tingyuan.,Wang, Qibao.,Zhang, Guifeng.,Huo, Junsheng.,...&Wang, Lianyan.(2016).Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,498(JUNE),128-138.
MLA Zhang, Bo,et al."Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 498.JUNE(2016):128-138.
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