| Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation | |
| Zhang, Liang1,2; Xu, Yanqing1; Xu, Jiandong1; Wei, Yuping1; Xu, Xia1 | |
| 2016-10-01 | |
| 发表期刊 | CELL PROLIFERATION
 |
| ISSN | 0960-7722 |
| 卷号 | 49期号:5页码:589-598 |
| 摘要 | ObjectivesHuman embryonic stem cells (hESCs) have huge potential for establishment of disease models and for treating degenerative diseases. However, the extremely low survival level of dissociated hESCs following cryopreservation is been a tremendous problem to allow for their rapid expansion, genetic manipulation and future medical applications. In this study, we have aimed to develop an efficient strategy to improve survival of dissociated hESCs after cryopreservation. |
| 文章类型 | Article |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1111/cpr.12278 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | ROCK INHIBITOR ; EFFICIENT CRYOPRESERVATION ; DEPENDENT APOPTOSIS ; HUMAN BLASTOCYSTS ; SELF-RENEWAL ; FREEZE-THAW ; DIFFERENTIATION ; EXPRESSION ; CULTURE ; MATRIX |
| WOS研究方向 | Cell Biology |
| WOS类目 | Cell Biology |
| 项目资助者 | National Natural Science Foundation of China(21176238 ; 21576266) |
| WOS记录号 | WOS:000383766400006 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.ipe.ac.cn/handle/122111/21334 |
| 专题 | 生化工程国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Liang,Xu, Yanqing,Xu, Jiandong,et al. Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation[J]. CELL PROLIFERATION,2016,49(5):589-598. |
| APA | Zhang, Liang,Xu, Yanqing,Xu, Jiandong,Wei, Yuping,&Xu, Xia.(2016).Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation.CELL PROLIFERATION,49(5),589-598. |
| MLA | Zhang, Liang,et al."Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation".CELL PROLIFERATION 49.5(2016):589-598. |
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| Zhang_et_al-2016-Cel（1239KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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