Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation | |
Zhang, Liang1,2; Xu, Yanqing1; Xu, Jiandong1; Wei, Yuping1; Xu, Xia1 | |
2016-10-01 | |
Source Publication | CELL PROLIFERATION
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ISSN | 0960-7722 |
Volume | 49Issue:5Pages:589-598 |
Abstract | ObjectivesHuman embryonic stem cells (hESCs) have huge potential for establishment of disease models and for treating degenerative diseases. However, the extremely low survival level of dissociated hESCs following cryopreservation is been a tremendous problem to allow for their rapid expansion, genetic manipulation and future medical applications. In this study, we have aimed to develop an efficient strategy to improve survival of dissociated hESCs after cryopreservation. |
Subtype | Article |
WOS Headings | Science & Technology ; Life Sciences & Biomedicine |
DOI | 10.1111/cpr.12278 |
Indexed By | SCI |
Language | 英语 |
WOS Keyword | ROCK INHIBITOR ; EFFICIENT CRYOPRESERVATION ; DEPENDENT APOPTOSIS ; HUMAN BLASTOCYSTS ; SELF-RENEWAL ; FREEZE-THAW ; DIFFERENTIATION ; EXPRESSION ; CULTURE ; MATRIX |
WOS Research Area | Cell Biology |
WOS Subject | Cell Biology |
Funding Organization | National Natural Science Foundation of China(21176238 ; 21576266) |
WOS ID | WOS:000383766400006 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ipe.ac.cn/handle/122111/21334 |
Collection | 生化工程国家重点实验室 |
Affiliation | 1.Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
Recommended Citation GB/T 7714 | Zhang, Liang,Xu, Yanqing,Xu, Jiandong,et al. Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation[J]. CELL PROLIFERATION,2016,49(5):589-598. |
APA | Zhang, Liang,Xu, Yanqing,Xu, Jiandong,Wei, Yuping,&Xu, Xia.(2016).Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation.CELL PROLIFERATION,49(5),589-598. |
MLA | Zhang, Liang,et al."Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation".CELL PROLIFERATION 49.5(2016):589-598. |
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