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Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation
Zhang, Liang1,2; Xu, Yanqing1; Xu, Jiandong1; Wei, Yuping1; Xu, Xia1
2016-10-01
发表期刊CELL PROLIFERATION
ISSN0960-7722
卷号49期号:5页码:589-598
摘要

ObjectivesHuman embryonic stem cells (hESCs) have huge potential for establishment of disease models and for treating degenerative diseases. However, the extremely low survival level of dissociated hESCs following cryopreservation is been a tremendous problem to allow for their rapid expansion, genetic manipulation and future medical applications. In this study, we have aimed to develop an efficient strategy to improve survival of dissociated hESCs after cryopreservation.

文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine
DOI10.1111/cpr.12278
收录类别SCI
语种英语
关键词[WOS]ROCK INHIBITOR ; EFFICIENT CRYOPRESERVATION ; DEPENDENT APOPTOSIS ; HUMAN BLASTOCYSTS ; SELF-RENEWAL ; FREEZE-THAW ; DIFFERENTIATION ; EXPRESSION ; CULTURE ; MATRIX
WOS研究方向Cell Biology
WOS类目Cell Biology
项目资助者National Natural Science Foundation of China(21176238 ; 21576266)
WOS记录号WOS:000383766400006
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ipe.ac.cn/handle/122111/21334
专题生化工程国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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GB/T 7714
Zhang, Liang,Xu, Yanqing,Xu, Jiandong,et al. Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation[J]. CELL PROLIFERATION,2016,49(5):589-598.
APA Zhang, Liang,Xu, Yanqing,Xu, Jiandong,Wei, Yuping,&Xu, Xia.(2016).Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation.CELL PROLIFERATION,49(5),589-598.
MLA Zhang, Liang,et al."Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation".CELL PROLIFERATION 49.5(2016):589-598.
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