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UV-curable enzymatic antibacterial waterborne polyurethane coating
Liu, Kai1,2; Su, Zhiguo1; Miao, Shida1; Ma, Guanghui1; Zhang, Songping1
2016-09-15
发表期刊BIOCHEMICAL ENGINEERING JOURNAL
ISSN1369-703X
卷号113期号:SEP页码:107-113
摘要

Novel ultraviolet (UV)-curable enzymatic antibacterial coatings were designed and fabricated. The coatings were prepared by simply mixture of castor oil-based cationic waterborne polyurethane-acrylate dispersion (WPUA) and acryloyl chloride modified lysozyme followed by UV curing. The covalent incorporation of lysozyme into the coatings was proved by enzyme leakage and IR analysis of the coatings. As the lysozyme content increased from 0 to 2.5% (w/w), the tensile strength of the coating enhanced by 37% (1.1 MPa vs 0.8 MPa), and the contact angle increased by 10% (73.1 degrees vs 80.6 degrees). Those changes are possibly due to enhancement of crosslinking degree and hydrogen. bonding induced by modified lysozyme. Based on live/dead staining and colonies number assay, the coatings containing lysozyme (2.5%, w/w) were highly efficient in killing Staphylococcus aureus (91.3%) and Escherichia coli (62.9%) via degradation of cell wall within 2 h, and the colonies number for both strains was significantly decreased to less than 1% after intubation for 24h. In addition, the killing efficiency of the coatings remained 68.3% after six continuous uses. Such UV-curable waterborne polyurethane coatings containing lysozyme (UWPU-L) may be useful in anti-bacterial stains on various common surfaces in hospital settings and food packaging. (C) 2016 Elsevier B.V. All rights reserved.

关键词Ultraviolet-curable Waterborne Polyurethane Lysozyme Antibacterial Coating
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Technology
DOI10.1016/j.bej.2016.06.004
收录类别SCI
语种英语
关键词[WOS]ANTIFOULING STRATEGIES ; LYSOZYME ; SURFACES ; ENZYMES ; MEMBRANES ; BACTERIAL ; HYDROGEL ; POLYMERS ; ADHESION ; FILMS
WOS研究方向Biotechnology & Applied Microbiology ; Engineering
WOS类目Biotechnology & Applied Microbiology ; Engineering, Chemical
项目资助者National Natural Science Foundation of China(21376249 ; 973 Program(2013CB733604) ; National Major Scientific Equipment Development Project(2013YQ14040508) ; 21336010 ; 91534126)
WOS记录号WOS:000380869600014
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ipe.ac.cn/handle/122111/21426
专题生化工程国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Liu, Kai,Su, Zhiguo,Miao, Shida,et al. UV-curable enzymatic antibacterial waterborne polyurethane coating[J]. BIOCHEMICAL ENGINEERING JOURNAL,2016,113(SEP):107-113.
APA Liu, Kai,Su, Zhiguo,Miao, Shida,Ma, Guanghui,&Zhang, Songping.(2016).UV-curable enzymatic antibacterial waterborne polyurethane coating.BIOCHEMICAL ENGINEERING JOURNAL,113(SEP),107-113.
MLA Liu, Kai,et al."UV-curable enzymatic antibacterial waterborne polyurethane coating".BIOCHEMICAL ENGINEERING JOURNAL 113.SEP(2016):107-113.
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