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Superparamagnetic Iron Oxide Nanoparticles as Magnetic Resonance Imaging Contrast Agent for Myocardial Infarction
Zeng, Mu1; Hu, Bingbing2,3; Chen, Jingli2,4; Zhang, Zhenzhong4; Zhang, Xin2; Fan, Zhanming1
2016-09-01
Source PublicationJOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING
ISSN2157-9083
Volume6Issue:9Pages:713-718
Abstract

Citric acid coated superparamagnetic iron oxide nanoparticles (CA-SPIONs) are synthesized by co-precipitation method and citric acid is used to stabilize nanoparticles and provide significantly small nanoparticles. CA-SPIONs have small size, favorable colloidal stability and excellent magnetic properties. As contrast agent, on the one hand CA-SPIONs have biocompatibility and can be endocytosed by macrophages, on the other hand CA-SPIONs have the ability of MRI in the infarcted tissue of myocardial infarction.

KeywordMyocardial Infarction Superparamagnetic Iron Oxide Nanoparticles Macrophages Infarcted Tissue Magnetic Resonance Imaging
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1166/jbt.2016.1500
Indexed BySCI
Language英语
WOS KeywordMACROPHAGE INFILTRATION ; CANCER-CELLS ; IN-VIVO ; ECHOCARDIOGRAPHY ; ENHANCEMENT ; TOMOGRAPHY ; ULTRASOUND ; DESIGN
WOS Research AreaCell Biology
WOS SubjectCell & Tissue Engineering
Funding OrganizationCapital University of Medical Science Affiliated Beijing Anzhen Hospital ; Institute of Process Engineering, Chinese Academy of Sciences
WOS IDWOS:000385537700006
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/21563
Collection生化工程国家重点实验室
Affiliation1.Capital Med Univ, Beijing Inst Heart Lung & Blood Vessel Dis, Beijing An Zhen Hosp, Dept Radiol, Beijing 100029, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
3.Ocean Univ China, Inst Mat Sci & Engn, Qingdao 266100, Shandong, Peoples R China
4.Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Henan, Peoples R China
Recommended Citation
GB/T 7714
Zeng, Mu,Hu, Bingbing,Chen, Jingli,et al. Superparamagnetic Iron Oxide Nanoparticles as Magnetic Resonance Imaging Contrast Agent for Myocardial Infarction[J]. JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING,2016,6(9):713-718.
APA Zeng, Mu,Hu, Bingbing,Chen, Jingli,Zhang, Zhenzhong,Zhang, Xin,&Fan, Zhanming.(2016).Superparamagnetic Iron Oxide Nanoparticles as Magnetic Resonance Imaging Contrast Agent for Myocardial Infarction.JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING,6(9),713-718.
MLA Zeng, Mu,et al."Superparamagnetic Iron Oxide Nanoparticles as Magnetic Resonance Imaging Contrast Agent for Myocardial Infarction".JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING 6.9(2016):713-718.
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