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Biomacromolecules based core/shell architecture toward biomedical applications
Cui, Wei1; Wang, Anhe2; Zhao, Jie1; Li, Junbai1
2016-11-01
Source PublicationADVANCES IN COLLOID AND INTERFACE SCIENCE
ISSN0001-8686
Volume237Issue:NOVPages:43-51
Abstract

Polyelectrolyte multilayer capsules have become a novel and promising class of hybrid materials with great potential since they can be applied in various areas, such as pharmaceutical sciences, biotechnology, and biomedicine. The concept of using such carriers for biology application is diagnosis and treatment of diseases for convenience, safety and specific targeting. Therefore, the development of biocompatible, biodegradable and specific characteristic nanostructure material is highly desirable. Much effort has been devoted to exploring innovative and effective techniques to fabricate such materials. Among the available techniques, layer-by-layer (LbL) assembly capsules have attracted considerable attention attributing to the flexibly controlled size, shape, composition, wall thickness and functions. Protein, as the large class of biomacromolecules, was incorporated into capsules for improving the biocompatibility and specific function. In this review we provide an overview of the recent progress in biomacromolecular capsules or core/shell architecture with different diameters for the variety of purposes. The size ranging from micro-, sub-micro to nano scale based on the choice of the template. Their advantages are discussed here. The applications of these biomacromolecular capsules in biotechnological fields have also been summarized, for instance blood substitute, ATP carriers, photodynamic therapy and nanomedicines. (C) 2016 Elsevier B.V. All rights reserved.

KeywordBiomacromolecules Core/shell Architecture Layer-by-layer Assembly Drug Carriers
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
DOI10.1016/j.cis.2016.10.001
Indexed BySCI
Language英语
WOS KeywordBY-LAYER NANOPARTICLES ; IN-VIVO ; DRUG-DELIVERY ; BLOOD SUBSTITUTES ; THERAPEUTIC NANOPARTICLES ; SELECTIVE RECOGNITION ; OXYGEN CARRIERS ; CANCER-THERAPY ; HEMOGLOBIN ; NANOARCHITECTONICS
WOS Research AreaChemistry
WOS SubjectChemistry, Physical
Funding OrganizationNational Nature Science Foundation of China(21433010 ; National Basic Research Program of China (973 program)(2013CB932800) ; 21320102004 ; 21503236 ; 21321063)
WOS IDWOS:000389107400004
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/21680
Collection生化工程国家重点实验室
Affiliation1.Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Cui, Wei,Wang, Anhe,Zhao, Jie,et al. Biomacromolecules based core/shell architecture toward biomedical applications[J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE,2016,237(NOV):43-51.
APA Cui, Wei,Wang, Anhe,Zhao, Jie,&Li, Junbai.(2016).Biomacromolecules based core/shell architecture toward biomedical applications.ADVANCES IN COLLOID AND INTERFACE SCIENCE,237(NOV),43-51.
MLA Cui, Wei,et al."Biomacromolecules based core/shell architecture toward biomedical applications".ADVANCES IN COLLOID AND INTERFACE SCIENCE 237.NOV(2016):43-51.
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