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Self-Assembled Peptide- and Protein-Based Nanomaterials for Antitumor Photodynamic and Photothermal Therapy
Abbas, Manzar1,2,3; Zou, Qianli1,2; Li, Shukun1,2,3; Yan, Xuehai1,2
2017-03-28
发表期刊ADVANCED MATERIALS
ISSN0935-9648
卷号29期号:12页码:1605021
摘要

Tremendous interest in self-assembly of peptides and proteins towards functional nanomaterials has been inspired by naturally evolving self-assembly in biological construction of multiple and sophisticated protein architectures in organisms. Self-assembled peptide and protein nanoarchitectures are excellent promising candidates for facilitating biomedical applications due to their advantages of structural, mechanical, and functional diversity and high biocompability and biodegradability. Here, this review focuses on the self-assembly of peptides and proteins for fabrication of phototherapeutic nanomaterials for antitumor photodynamic and photothermal therapy, with emphasis on building blocks, non-covalent interactions, strategies, and the nanoarchitectures of self-assembly. The exciting antitumor activities achieved by these phototherapeutic nanomaterials are also discussed in-depth, along with the relationships between their specific nanoarchitectures and their unique properties, providing an increased understanding of the role of peptide and protein self-assembly in improving the efficiency of photodynamic and photothermal therapy.

文章类型Article
WOS标题词Science & Technology ; Physical Sciences ; Technology
DOI10.1002/adma.201605021
收录类别SCI
语种英语
关键词[WOS]SERUM-ALBUMIN NANOPARTICLES ; TARGETED CHIMERIC PEPTIDE ; DRUG-DELIVERY SYSTEMS ; CANCER-THERAPY ; IN-VITRO ; DIPHENYLALANINE PEPTIDE ; FERRITIN NANOCAGES ; INDOCYANINE GREEN ; TUMOR ; NANOARCHITECTONICS
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
项目资助者National Natural Science Foundation of China(21522307 ; Talent Fund of the Recruitment Program of Global Youth Experts ; Chinese Academy of Sciences (CAS)(QYZDB-SSW-JSC034) ; 21473208 ; 51403214 ; 91434103)
WOS记录号WOS:000396998800009
引用统计
被引频次:92[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ipe.ac.cn/handle/122111/22003
专题生化工程国家重点实验室
作者单位1.Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Ctr Mesosci, Inst Proc Engn, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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GB/T 7714
Abbas, Manzar,Zou, Qianli,Li, Shukun,et al. Self-Assembled Peptide- and Protein-Based Nanomaterials for Antitumor Photodynamic and Photothermal Therapy[J]. ADVANCED MATERIALS,2017,29(12):1605021.
APA Abbas, Manzar,Zou, Qianli,Li, Shukun,&Yan, Xuehai.(2017).Self-Assembled Peptide- and Protein-Based Nanomaterials for Antitumor Photodynamic and Photothermal Therapy.ADVANCED MATERIALS,29(12),1605021.
MLA Abbas, Manzar,et al."Self-Assembled Peptide- and Protein-Based Nanomaterials for Antitumor Photodynamic and Photothermal Therapy".ADVANCED MATERIALS 29.12(2017):1605021.
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