CAS OpenIR  > 多相复杂系统国家重点实验室
Quantitative Change in Disulfide Bonds and Microstructure Variation of Regenerated Wool Keratin from Various Ionic Liquids
Zhang, Zhenlei1,2; Nie, Yi1; Zhang, Qiansen1; Liu, Xue3; Tu, Wenhui1,2; Zhang, Xiangping1; Zhang, Suojiang1
2017-03-01
Source PublicationACS SUSTAINABLE CHEMISTRY & ENGINEERING
ISSN2168-0485
Volume5Issue:3Pages:2614-2622
Abstract

Ionic liquids (ILs) have been employed as solvents for dissolving wool keratin which can be further regenerated and applied in high-value and biocompatible keratin-based materials. It is urgent to determine the changes in disulfide bonds and keratin microstructures in the dissolution process for designing efficient ILs. Herein, the breakage of disulfide bonds by ILs was verified for the first time using a model compound, oxidized glutathione. Furthermore, at least 65% of disulfide bonds in keratin should be cleaved in order to be dissolved in ILs. The keratin regenerated in a series of ILs, and variable conditions were also characterized by a combination of S-linked techniques. The results indicated that changing both anions and cations can lead to a dramatically different ability to cleave disulfide bonds, while the side chains of the cations have little effect on it. Also, the dissolution variables, such as temperature and time, led to different amounts of disulfide bonds remaining in the regenerated keratin. Finally, molecular dynamics (MD) simulation found that the distribution of ILs around cystine was linked with the ILs' disulfide bond cleaving ability.

KeywordWool Keratin Ionic Liquids Disulfide Bond Network Cleavage
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences ; Technology
DOI10.1021/acssuschemeng.6b02963
Indexed BySCI
Language英语
WOS KeywordGeneral Force-field ; Feather Keratin ; Extractive Desulfurization ; Highly Efficient ; Solid-state ; Dissolution ; Disentanglement ; Automation ; Algorithms ; Simulation
WOS Research AreaChemistry ; Engineering
WOS SubjectChemistry, Multidisciplinary ; Engineering, Chemical
Funding OrganizationNational Natural Science Foundation of China(21576262) ; National Natural Science Fund for Distinguished Young Scholars(21425625) ; International Cooperation and Exchange of the National Natural Science Foundation of China(51561145020)
WOS IDWOS:000395846900065
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/22085
Collection多相复杂系统国家重点实验室
Affiliation1.Chinese Acad Sci, Beijing Key Lab Ion Liquids Clean Proc, State Key Lab Multiphase Complex Syst, Key Lab Green Proc & Engn,Inst Proc Engn, 1 North Second St, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Sch Chem & Chem Engn, 19 A Yuquan Rd, Beijing 100049, Peoples R China
3.Qufu Normal Univ, Coll Chem & Chem Engn, 57 Jingxuan West Rd, Jining 273165, Shandong, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Zhenlei,Nie, Yi,Zhang, Qiansen,et al. Quantitative Change in Disulfide Bonds and Microstructure Variation of Regenerated Wool Keratin from Various Ionic Liquids[J]. ACS SUSTAINABLE CHEMISTRY & ENGINEERING,2017,5(3):2614-2622.
APA Zhang, Zhenlei.,Nie, Yi.,Zhang, Qiansen.,Liu, Xue.,Tu, Wenhui.,...&Zhang, Suojiang.(2017).Quantitative Change in Disulfide Bonds and Microstructure Variation of Regenerated Wool Keratin from Various Ionic Liquids.ACS SUSTAINABLE CHEMISTRY & ENGINEERING,5(3),2614-2622.
MLA Zhang, Zhenlei,et al."Quantitative Change in Disulfide Bonds and Microstructure Variation of Regenerated Wool Keratin from Various Ionic Liquids".ACS SUSTAINABLE CHEMISTRY & ENGINEERING 5.3(2017):2614-2622.
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