CAS OpenIR  > 生化工程国家重点实验室
Simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum by combined column chromatography
Liu, Boyan1,2; Dong, Beitao1,2; Yuan, Xiaofan1; Guo, Yuanheng1,2; Zhang, Lijun1,2; Zhao, Bing1
2017
Source PublicationSEPARATION SCIENCE AND TECHNOLOGY
ISSN0149-6395
Volume52Issue:6Pages:1114-1121
Abstract

An efficient method for simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum was developed. The entire procedure consisted of two separation steps. The first step was enrichment of chlorogenic acid from the crude extract by NKA-II macroporous resin. The purity of chlorogenic acid increased from 5.3% to 20.9% with a recovery of 88.7%. Subsequently, polyamide resin was used to achieve a higher purity. After the polyamide resin treatment, the main toxin 9-oxo-10,11-dehydroageraphorone was removed and the purity of chlorogenic acid reached 86.5% with a recovery of 84.8%. It provided a new way for the utilization of E. adenophorum.

KeywordChlorogenic Acid Eupatorium Adenophorum Spreng Macroporous Resin 9-oxo-10 11-dehydroageraphorone Polyamide Resin
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences ; Technology
DOI10.1080/01496395.2017.1281300
Indexed BySCI
Language英语
WOS KeywordPerformance Liquid-chromatography ; Counter-current Chromatography ; Polyamide Resin ; Macroporous Resins ; Ageratina-adenophora ; Caffeic Acid ; Natural-products ; Purification ; Adsorption ; Extract
WOS Research AreaChemistry ; Engineering
WOS SubjectChemistry, Multidisciplinary ; Engineering, Chemical
Funding OrganizationPanzhihua Xiyu Biotech Co., Ltd. ( Sichuan, China)
WOS IDWOS:000399643200014
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/22477
Collection生化工程国家重点实验室
Affiliation1.Chinese Acad Sci, Inst Proc Engn, Div Biorefinery Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Liu, Boyan,Dong, Beitao,Yuan, Xiaofan,et al. Simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum by combined column chromatography[J]. SEPARATION SCIENCE AND TECHNOLOGY,2017,52(6):1114-1121.
APA Liu, Boyan,Dong, Beitao,Yuan, Xiaofan,Guo, Yuanheng,Zhang, Lijun,&Zhao, Bing.(2017).Simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum by combined column chromatography.SEPARATION SCIENCE AND TECHNOLOGY,52(6),1114-1121.
MLA Liu, Boyan,et al."Simultaneous detoxification and preparative separation of chlorogenic acid from Eupatorium adenophorum by combined column chromatography".SEPARATION SCIENCE AND TECHNOLOGY 52.6(2017):1114-1121.
Files in This Item:
File Name/Size DocType Version Access License
Simultaneous detoxif(12920KB)期刊论文出版稿限制开放CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu, Boyan]'s Articles
[Dong, Beitao]'s Articles
[Yuan, Xiaofan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu, Boyan]'s Articles
[Dong, Beitao]'s Articles
[Yuan, Xiaofan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu, Boyan]'s Articles
[Dong, Beitao]'s Articles
[Yuan, Xiaofan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.