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Immobilization of native type I collagen on polypropylene fabrics as a substrate for HepG2 cell culture
Peng, Gongze1; Li, Saina2; Peng, Qing1; Li, Yang1; Weng, Jun1; Jia, Zhidong1; Kang, Jiyao2; Lei, Xiongxin2; Zhang, Guifeng2; Gao, Yi1,3
2017-07-01
Source PublicationJOURNAL OF BIOMATERIALS APPLICATIONS
ISSN0885-3282
Volume32Issue:1Pages:93-103
Abstract

Background/aims The critical part of a bio-artificial liver device is establishment of a bioreactor filled with liver cells. However, it is still unclear how to maintain benign cell function while achieving the sufficient cell quantity. In the current study, we aim to establish a novel carrier for the culture of HepG2 cells, a liver cell line, by modifying polypropylene nonwoven fabrics with native type I collagen.

KeywordPolypropylene Nonwoven Fabrics Surface Modification Hepatocyte Cell Proliferation Collagen
SubtypeArticle
WOS HeadingsScience & Technology ; Technology
DOI10.1177/0885328217709607
Indexed BySCI
Language英语
WOS KeywordArtificial Liver Support ; Engineering Recent Advances ; Bioartificial Liver ; Hepatic Differentiation ; Surface Modification ; Failure ; Microcarriers ; Scaffold ; Feasibility ; Survival
WOS Research AreaEngineering ; Materials Science
WOS SubjectEngineering, Biomedical ; Materials Science, bioMaterials
Funding OrganizationNational Natural Science Foundation of China(81470875) ; Natural Science Foundation of Guangdong Province(2014A030312013) ; Science and Technology Planning Project of Guangdong Province(2014B020227002 ; 2015B090903069 ; 2015B020229002)
WOS IDWOS:000403604200009
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/22710
Collection生化工程国家重点实验室
Affiliation1.Southern Med Univ, Zhujiang Hosp, Dept Hepatobiliary Surg 2, Guangdong Prov Res Ctr Artificial Organ & Tissue, Guangzhou, Guangdong, Peoples R China
2.Inst Proc Engn, Natl Key Lab Biochem Engn, 1 Bei Er Tiao, Beijing 100190, Peoples R China
3.Southern Med Univ, State Key Lab Organ Failure Res, Guangzhou, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Peng, Gongze,Li, Saina,Peng, Qing,et al. Immobilization of native type I collagen on polypropylene fabrics as a substrate for HepG2 cell culture[J]. JOURNAL OF BIOMATERIALS APPLICATIONS,2017,32(1):93-103.
APA Peng, Gongze.,Li, Saina.,Peng, Qing.,Li, Yang.,Weng, Jun.,...&Gao, Yi.(2017).Immobilization of native type I collagen on polypropylene fabrics as a substrate for HepG2 cell culture.JOURNAL OF BIOMATERIALS APPLICATIONS,32(1),93-103.
MLA Peng, Gongze,et al."Immobilization of native type I collagen on polypropylene fabrics as a substrate for HepG2 cell culture".JOURNAL OF BIOMATERIALS APPLICATIONS 32.1(2017):93-103.
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