Tuning Supramolecular Structure and Functions of Peptide bola-Amphiphile by Solvent Evaporation-Dissolution

doi:10.1021/acsami.7b05661

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	Tuning Supramolecular Structure and Functions of Peptide bola-Amphiphile by Solvent Evaporation-Dissolution
	Wang, Anhe 1; Cui, Lingyun 1; Debnath, Sisir 2; Dong, Qianqian 1; Yan, Xuehai 1; Zhang, Xi 3; Ulijn, Rein V.2,4,5,6; Bai, Shuo 1
	2017-06-28
发表期刊	ACS APPLIED MATERIALS & INTERFACES
ISSN	1944-8244
卷号	9 期号:25 页码:21390-21396
摘要	Solvent molecules significantly affect the supramolecular self-assembly, for example, in forming solvent-bridged hydrogen bonding networks. Even small changes in solvent composition can have dramatic impact on supramolecular assembly. Herein, we demonstrate the use of trace solvents (as low as 0.04%) to tune the morphology and consequent functions of supramolecular nanostructures based on an aromatic peptide bola-amphiphile. Specifically, perylene bisimide-(di)glycine-tyrosine (PBI-[GY](2)) bola-amphiphile was shown to give rise to red-emitting nanofibers when assembled in water, while exposure to trace organic solvents such as tetrahydrofuran (THF) and others via solvent-evaporation followed by aqueous assembly gave rise to white-light-emitting nanospheres. Differential hydrogen bonding between water (donor and acceptor) and THF (acceptor only) impacts supramolecular organization, which was verified using a density functional theory (DFT) simulation. The tunable consequent surface hydrophobicity was utilized in staining the cytoplasm and membrane of cells, respectively. The trace-solvent effect achieved through evaporationdissolution provides a methodology to mediate the morphologies and consequent functions for supramolecular biomaterials controlled by the self-assembly pathway.
关键词	Trace Solvent Peptide Self-assembly Nanostructure White Light Emission Cell Staining
文章类型	Article
WOS标题词	Science & Technology ; Technology
DOI	10.1021/acsami.7b05661
收录类别	SCI
语种	英语
关键词[WOS]	PERYLENE BISIMIDE ; LIVE CELLS ; WATER ; BIOMATERIALS ; FABRICATION ; MATTER
WOS研究方向	Science & Technology - Other Topics ; Materials Science
WOS类目	Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
项目资助者	National Natural Science Foundation of China(21644007) ; Talent Fund of the Recruitment Program of Global Youth Experts
WOS记录号	WOS:000404807200040
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ipe.ac.cn/handle/122111/22800
专题	生化工程国家重点实验室
作者单位	1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Strathclyde, Dept Pure & Appl Chem, WestCHEM, Glasgow G1 1XL, Lanark, Scotland 3.Tsinghua Univ, Dept Chem, MOE Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China 4.CUNY, ASRC, New York, NY 10031 USA 5.CUNY Hunter Coll, Dept Chem & Biochem, 695 Pk Ave, New York, NY 10065 USA 6.CUNY, Grad Ctr, New York, NY 10016 USA
推荐引用方式 GB/T 7714	Wang, Anhe,Cui, Lingyun,Debnath, Sisir,et al. Tuning Supramolecular Structure and Functions of Peptide bola-Amphiphile by Solvent Evaporation-Dissolution[J]. ACS APPLIED MATERIALS & INTERFACES,2017,9(25):21390-21396.
APA	Wang, Anhe.,Cui, Lingyun.,Debnath, Sisir.,Dong, Qianqian.,Yan, Xuehai.,...&Bai, Shuo.(2017).Tuning Supramolecular Structure and Functions of Peptide bola-Amphiphile by Solvent Evaporation-Dissolution.ACS APPLIED MATERIALS & INTERFACES,9(25),21390-21396.
MLA	Wang, Anhe,et al."Tuning Supramolecular Structure and Functions of Peptide bola-Amphiphile by Solvent Evaporation-Dissolution".ACS APPLIED MATERIALS & INTERFACES 9.25(2017):21390-21396.