CAS OpenIR  > 生化工程国家重点实验室
A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles
Qu, Hongnan1,2,3,4; Yang, Liangrong2; Yu, Jiemiao2; Dong, Tingting2,3; Rong, Meng2,3; Zhang, Jianfeng2,3,4; Xing, Huifang2; Wang, Li2; Pan, Feng2; Liu, Huizhou2
2017
发表期刊RSC ADVANCES
ISSN2046-2069
卷号7期号:57页码:35704-35710
摘要

A novel redox responsive controlled release system based on the host-guest interaction between ferrocene modified mesoporous silica nanoparticles (MSN-Fc) and beta-cyclodextrin modified gold nanoparticles (Au@CD) was developed. FITC was used as the release molecule and it was loaded into the pores of MSN-Fc. With the addition of oxidant (H2O2), oxidized ferrocene leaves the hydrophobic cavity of b-CD, resulting in cargo controlled release. Due to the structural properties of the modified MSN, the continuously slow release behavior showed the prospect to be a sustained drug delivery system. This novel redox responsive system possessed stimuli-responsive controlled release and sustained release properties, and therefore has potential applications in sustained and targeted drug delivery.

文章类型Article
WOS标题词Science & Technology ; Physical Sciences
DOI10.1039/c7ra04444e
收录类别SCI
语种英语
关键词[WOS]OPERATED MECHANIZED NANOPARTICLES ; DRUG-DELIVERY ; MAGNETIC NANOPARTICLES ; GUEST MOLECULES ; CARGO RELEASE ; IN-VITRO ; PH ; NANOVALVES ; ENZYME ; NANOCARRIERS
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
项目资助者National Natural Science Foundation of China(21676273) ; National Key Natural Science Foundation of China(U1507203) ; National Technology Research and Development Program of China(2015CB251402) ; Youth Innovation Promotion Association, CAS(2016043)
WOS记录号WOS:000406104300018
引用统计
文献类型期刊论文
条目标识符http://ir.ipe.ac.cn/handle/122111/22982
专题生化工程国家重点实验室
作者单位1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Sinodanish Ctr Educ & Res, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Qu, Hongnan,Yang, Liangrong,Yu, Jiemiao,et al. A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles[J]. RSC ADVANCES,2017,7(57):35704-35710.
APA Qu, Hongnan.,Yang, Liangrong.,Yu, Jiemiao.,Dong, Tingting.,Rong, Meng.,...&Liu, Huizhou.(2017).A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles.RSC ADVANCES,7(57),35704-35710.
MLA Qu, Hongnan,et al."A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles".RSC ADVANCES 7.57(2017):35704-35710.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
A redox responsive c(659KB)期刊论文出版稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Qu, Hongnan]的文章
[Yang, Liangrong]的文章
[Yu, Jiemiao]的文章
百度学术
百度学术中相似的文章
[Qu, Hongnan]的文章
[Yang, Liangrong]的文章
[Yu, Jiemiao]的文章
必应学术
必应学术中相似的文章
[Qu, Hongnan]的文章
[Yang, Liangrong]的文章
[Yu, Jiemiao]的文章
相关权益政策
暂无数据
收藏/分享
文件名: A redox responsive controlled release system using mesoporous silica nanoparticles capped with Au nanoparticles.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。