Aggregation-Induced-Emission Materials with Different Electric Charges as an Artificial Tongue: Design, Construction, and Assembly with Various Pathogenic Bacteria for Effective Bacterial Imaging and Discrimination | |
Liu, Guang-jian1; Tian, Sheng-nan2,3; Li, Cui-yun1; Xing, Guo-wen2; Zhou, Lei2,3 | |
2017-08-30 | |
Source Publication | ACS APPLIED MATERIALS & INTERFACES
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ISSN | 1944-8244 |
Volume | 9Issue:34Pages:28331-28338 |
Abstract | Imaging-based total bacterial count and type identification of bacteria play crucial roles in clinical diagnostics; public health, biological and medical science, and environmental protection. Herein, we designed and synthesized a series of tetraphenylethenes (TPEs) functionalized with one or two aldehyde, carboxylic acid, and quaternary ammonium groups, which were successfully used as fluorescent materials for rapid and efficient staining of eight kinds of reptesentative bacterial species, including pathogenic bacteria Vibrio cholera, Klebsiella pneumoniae, and Listeria monocytogenes and potential bioterrorism agent Yersinia pestis. By comparing the fluorescence intensity changes of the aggregation-induced-erinssion (AIE) materials before and after bacteria incubation, the sensing mechanisms (electrostatic versus hydrophobic interactions) were simply discussed. Moreover, the designed AIE materials were successfully used as an efficient artificial tongue for bacteria discrimination, and all of the bacteria tested were identified via linear discriminant analysis. Our current work provided a general method for simultaneous broad-spectrum bacterial imaging and species discrimination, which is helpful for bacteria surveillance in many fields. |
Keyword | Tetraphenylethene Aggregation-induced Emission Linear Discrimination Analysis Bacterial Imaging Bacterial Discrimination |
Subtype | Article |
WOS Headings | Science & Technology ; Technology |
DOI | 10.1021/acsami.7b09848 |
Indexed By | SCI |
Language | 英语 |
WOS Keyword | Microbial Pathogens ; Aie Luminogen ; Sensor Arrays ; Living Cells ; Fluorescent ; Identification ; Probe ; Polymers ; Assay ; Wall |
WOS Research Area | Science & Technology - Other Topics ; Materials Science |
WOS Subject | Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
Funding Organization | National Natural Science Foundation of China(21272027) ; National Key Research and Development Program of China(2016YFC1202502) ; National High Technology Research and Development Program of China (863 Program)(2013AA032205) ; Beijing Nova Program of China(Z151100000315086) |
WOS ID | WOS:000409395500021 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ipe.ac.cn/handle/122111/23231 |
Collection | 生化工程国家重点实验室 |
Affiliation | 1.Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, PLA Key Lab Biopharmaceut Prod & Formulat Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 3.Beijing Inst Microbiol & Epidemiol, State Key Lab Pathogen & Biosecur, Beijing 100071, Peoples R China |
Recommended Citation GB/T 7714 | Liu, Guang-jian,Tian, Sheng-nan,Li, Cui-yun,et al. Aggregation-Induced-Emission Materials with Different Electric Charges as an Artificial Tongue: Design, Construction, and Assembly with Various Pathogenic Bacteria for Effective Bacterial Imaging and Discrimination[J]. ACS APPLIED MATERIALS & INTERFACES,2017,9(34):28331-28338. |
APA | Liu, Guang-jian,Tian, Sheng-nan,Li, Cui-yun,Xing, Guo-wen,&Zhou, Lei.(2017).Aggregation-Induced-Emission Materials with Different Electric Charges as an Artificial Tongue: Design, Construction, and Assembly with Various Pathogenic Bacteria for Effective Bacterial Imaging and Discrimination.ACS APPLIED MATERIALS & INTERFACES,9(34),28331-28338. |
MLA | Liu, Guang-jian,et al."Aggregation-Induced-Emission Materials with Different Electric Charges as an Artificial Tongue: Design, Construction, and Assembly with Various Pathogenic Bacteria for Effective Bacterial Imaging and Discrimination".ACS APPLIED MATERIALS & INTERFACES 9.34(2017):28331-28338. |
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Aggregation-Induced-(3152KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | Application Full Text |
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