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alpha, omega-Dodecanedioic acid production by Candida viswanathii ipe-1 with co-utilization of wheat straw hydrolysates and n-dodecane
Cao, Weifeng1; Liu, Bin2; Luo, Jianquan1; Yin, Junxiang3; Wan, Yinhua1
2017-11-01
发表期刊BIORESOURCE TECHNOLOGY
ISSN0960-8524
卷号243期号:NOV页码:179-187
摘要

Candida viswanathii ipe-1 was used to produce alpha, omega-dodecanedioic acid (DC12), which showed capability to ferment xylose and glucose simultaneously, while arabinose utilization was less efficient. A low concentration of furfural enhanced cell growth, and the addition of 4.0 g/L sodium acetate largely increased DC12 production. It indicated that detoxification of the wheat straw hydrolysates was not necessary for the biosynthesis of DC12. Based on the promising features of our strain, an efficient process was developed to produce DC12 from co-utilization of wheat straw hydrolysates and n-dodecane. Using this process, 129.7 g/L DC12 with a corresponding productivity of 1.13 g.L-1.h(-1) could be produced, which was increased by 40.0% compared with a sole carbon of glucose. The improved DC12 yield by the coutilization of wheat straw hydrolysates and n-dodecane using C. viswanathii ipe-1 demonstrates the great potential of using biomass as a feedstock in the production of DC12. (C) 2017 Elsevier Ltd. All rights reserved.

关键词Candida Viswanathii Alpha Wheat Straw Omega-dodecanedioic Acid N-dodecane
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Technology
DOI10.1016/j.biortech.2017.06.082
收录类别SCI
语种英语
关键词[WOS]CHAIN DICARBOXYLIC-ACIDS ; CARBONYL REDUCTASE PRODUCTION ; DILUTE-ACID ; FATTY-ACIDS ; BY-PRODUCTS ; TROPICALIS ; FERMENTATION ; ALKANES ; CELLS ; LIGNOCELLULOSE
WOS研究方向Agriculture ; Biotechnology & Applied Microbiology ; Energy & Fuels
WOS类目Agricultural Engineering ; Biotechnology & Applied Microbiology ; Energy & Fuels
项目资助者National High Technology Research and Development Program of China(2015AA021002 ; National Natural Science Foundation of China(21406240) ; 2014AA021005)
WOS记录号WOS:000411239300021
引用统计
文献类型期刊论文
条目标识符http://ir.ipe.ac.cn/handle/122111/23242
专题生化工程国家重点实验室
作者单位1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Qilu Univ Technol, Coll Food Sci & Engn, Jinan 250353, Shandong, Peoples R China
3.China Natl Ctr Biotechnol Dev, Beijing 100036, Peoples R China
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Cao, Weifeng,Liu, Bin,Luo, Jianquan,et al. alpha, omega-Dodecanedioic acid production by Candida viswanathii ipe-1 with co-utilization of wheat straw hydrolysates and n-dodecane[J]. BIORESOURCE TECHNOLOGY,2017,243(NOV):179-187.
APA Cao, Weifeng,Liu, Bin,Luo, Jianquan,Yin, Junxiang,&Wan, Yinhua.(2017).alpha, omega-Dodecanedioic acid production by Candida viswanathii ipe-1 with co-utilization of wheat straw hydrolysates and n-dodecane.BIORESOURCE TECHNOLOGY,243(NOV),179-187.
MLA Cao, Weifeng,et al."alpha, omega-Dodecanedioic acid production by Candida viswanathii ipe-1 with co-utilization of wheat straw hydrolysates and n-dodecane".BIORESOURCE TECHNOLOGY 243.NOV(2017):179-187.
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