Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield

doi:10.1016/j.foodchem.2017.11.083

CAS OpenIR > 研究所（批量导入）

	Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield
	Zhao, Dong 1,2; Xu, Jian 1,3; Xu, Xia 1,3; Xu, X
	2018-04-15
发表期刊	FOOD CHEMISTRY
ISSN	0308-8146
卷号	245 期号:00 页码:911-918
摘要	Due to antitumor and antioxidant activities, there has been increasing interest in fucoidans, sulfated polysaccharides, from brown algae. Currently, the classic hot water extraction and acid extraction are time-consuming, and can cause the partial cleavage of sulfate esters, leading to bioactivity loss. The present study developed a novel process for extracting fucoidans from Laminaria japonica with 0.5% ethylenediaminetetraacetic acid at 70 degrees C. Crude fucoidans (CFs) obtained with a yield (similar to 16%) was purified to different fractions of F1, F2 and F3. The fractions displayed similar anticancer activity against Hela cells. Due to the differences in sulfate content, molar ratio of sulfate to fucose and monosaccharide composition, F1 and F2 exhibited stronger antioxidant ability than CFs and F3. This novel extraction provides an efficient procedure for extracting fucoidans from brown seaweeds with high extraction yield and removing pigments with one single step.
关键词	Sulfated Polysaccharides Fucoidan Extraction Antioxidant Activity Antitumor Activity Pigments
文章类型	Article
WOS标题词	Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine
DOI	10.1016/j.foodchem.2017.11.083
收录类别	SCI
语种	英语
关键词[WOS]	Containing Sulfated Polysaccharides ; Microwave-assisted Extraction ; Antioxidant Activity ; Brown Seaweed ; Undaria-pinnatifida ; In-vitro ; Emulsifying Activities ; Potential Antioxidant ; Ascophyllum-nodosum ; Antiviral Activity
WOS研究方向	Chemistry ; Food Science & Technology ; Nutrition & Dietetics
WOS类目	Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics
项目资助者	National Natural Science Foundation of China(21576266 ; Major Research plan of the National Natural Science Foundation of China(91534107) ; Wanjiang Scholar Program ; Start Fund for Biochemical Engineering Center from Anhui University of Technology ; 21176238)
WOS记录号	WOS:000418471100113
引用统计
文献类型	期刊论文
条目标识符	http://ir.ipe.ac.cn/handle/122111/23448
专题	研究所（批量导入）
通讯作者	Xu, X
作者单位	1.Anhui Univ Technol, Sch Chem & Chem Engn, Biochem Engn Res Ctr, 59 Hudong St, Maanshan 243032, Anhui, Peoples R China 2.Beijing Univ Chem Technol, Coll Chem Engn, Beijing 100029, Peoples R China 3.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Dong,Xu, Jian,Xu, Xia,et al. Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield[J]. FOOD CHEMISTRY,2018,245(00):911-918.
APA	Zhao, Dong,Xu, Jian,Xu, Xia,&Xu, X.(2018).Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield.FOOD CHEMISTRY,245(00),911-918.
MLA	Zhao, Dong,et al."Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield".FOOD CHEMISTRY 245.00(2018):911-918.