Knowledge Management System Of Institute of process engineering,CAS
Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield | |
Zhao, Dong1,2; Xu, Jian1,3; Xu, Xia1,3; Xu, X | |
2018-04-15 | |
Source Publication | FOOD CHEMISTRY
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ISSN | 0308-8146 |
Volume | 245Issue:00Pages:911-918 |
Abstract | Due to antitumor and antioxidant activities, there has been increasing interest in fucoidans, sulfated polysaccharides, from brown algae. Currently, the classic hot water extraction and acid extraction are time-consuming, and can cause the partial cleavage of sulfate esters, leading to bioactivity loss. The present study developed a novel process for extracting fucoidans from Laminaria japonica with 0.5% ethylenediaminetetraacetic acid at 70 degrees C. Crude fucoidans (CFs) obtained with a yield (similar to 16%) was purified to different fractions of F1, F2 and F3. The fractions displayed similar anticancer activity against Hela cells. Due to the differences in sulfate content, molar ratio of sulfate to fucose and monosaccharide composition, F1 and F2 exhibited stronger antioxidant ability than CFs and F3. This novel extraction provides an efficient procedure for extracting fucoidans from brown seaweeds with high extraction yield and removing pigments with one single step. |
Keyword | Sulfated Polysaccharides Fucoidan Extraction Antioxidant Activity Antitumor Activity Pigments |
Subtype | Article |
WOS Headings | Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine |
DOI | 10.1016/j.foodchem.2017.11.083 |
Indexed By | SCI |
Language | 英语 |
WOS Keyword | Containing Sulfated Polysaccharides ; Microwave-assisted Extraction ; Antioxidant Activity ; Brown Seaweed ; Undaria-pinnatifida ; In-vitro ; Emulsifying Activities ; Potential Antioxidant ; Ascophyllum-nodosum ; Antiviral Activity |
WOS Research Area | Chemistry ; Food Science & Technology ; Nutrition & Dietetics |
WOS Subject | Chemistry, Applied ; Food Science & Technology ; Nutrition & Dietetics |
Funding Organization | National Natural Science Foundation of China(21576266 ; Major Research plan of the National Natural Science Foundation of China(91534107) ; Wanjiang Scholar Program ; Start Fund for Biochemical Engineering Center from Anhui University of Technology ; 21176238) |
WOS ID | WOS:000418471100113 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ipe.ac.cn/handle/122111/23448 |
Collection | 研究所(批量导入) |
Corresponding Author | Xu, X |
Affiliation | 1.Anhui Univ Technol, Sch Chem & Chem Engn, Biochem Engn Res Ctr, 59 Hudong St, Maanshan 243032, Anhui, Peoples R China 2.Beijing Univ Chem Technol, Coll Chem Engn, Beijing 100029, Peoples R China 3.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China |
Recommended Citation GB/T 7714 | Zhao, Dong,Xu, Jian,Xu, Xia,et al. Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield[J]. FOOD CHEMISTRY,2018,245(00):911-918. |
APA | Zhao, Dong,Xu, Jian,Xu, Xia,&Xu, X.(2018).Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield.FOOD CHEMISTRY,245(00),911-918. |
MLA | Zhao, Dong,et al."Bioactivity of fucoidan extracted from Laminaria japonica using a novel procedure with high yield".FOOD CHEMISTRY 245.00(2018):911-918. |
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Bioactivity of fucoi(1017KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | Application Full Text |
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