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Engineering and delivery of nanocolloids of hydrophobic drugs
Zhao, Luyang1; Shen, Guizhi1,2; Ma, Guanghui1; Yan, Xuehai1,2
2017-11-01
Source PublicationADVANCES IN COLLOID AND INTERFACE SCIENCE
ISSN0001-8686
Volume249Issue:00Pages:308-320
Abstract

A lot of efforts have been devoted to engineering the delivery of hydrophobic drugs due to the high demand of chemotherapy against cancer. While early developed liposomes and polymeric nanoparticles did not meet the requirements of high drug loading efficiency, pure drug nanoparticles appeared to meet these together with high stability. Current drug delivery systems demand an improved performance over the whole aspects of stability, loading capacity, and therapeutic effects. As a result, both new techniques based on traditional methods and totally new procedures are under investigation. In this review, we focus on the evaluation of pure drug nanolloids fabricated by different engineering protocols with emphasis on the size and morphology, delivery and controlled release, and therapeutic effects of these drug nanocolloids.

KeywordNanocolloids Hydrophobic Drugs Delivery And Controlled Release Ostwald Ripening Suppression Nanoengineering
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
DOI10.1016/j.cis.2017.04.008
Indexed BySCI
Language英语
WOS KeywordMesoporous Silica Nanoparticles ; Dipeptide-based Nanocarriers ; Flash Nanoprecipitation ; Photodynamic Therapy ; Cancer-therapy ; Antitumor Therapy ; Pure Nanodrugs ; Carrier-free ; In-vitro ; Stability
WOS Research AreaChemistry
WOS SubjectChemistry, Physical
Funding OrganizationNational Natural Science Foundation of China(21522307 ; Talent Fund of the Recruitment Program of Global Youth Experts ; Chinese Academy of Sciences(QYZDB-SSW-JSC034) ; 21473208 ; 21603233 ; 91434103)
WOS IDWOS:000418316500020
Citation statistics
Cited Times:12[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/23507
Collection研究所(批量导入)
Corresponding AuthorYan, Xuehai
Affiliation1.Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Ctr Mesosci, Inst Proc Engn, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Zhao, Luyang,Shen, Guizhi,Ma, Guanghui,et al. Engineering and delivery of nanocolloids of hydrophobic drugs[J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE,2017,249(00):308-320.
APA Zhao, Luyang,Shen, Guizhi,Ma, Guanghui,&Yan, Xuehai.(2017).Engineering and delivery of nanocolloids of hydrophobic drugs.ADVANCES IN COLLOID AND INTERFACE SCIENCE,249(00),308-320.
MLA Zhao, Luyang,et al."Engineering and delivery of nanocolloids of hydrophobic drugs".ADVANCES IN COLLOID AND INTERFACE SCIENCE 249.00(2017):308-320.
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