CAS OpenIR  > 生化工程国家重点实验室
Preparation and Application of Porous Polymer Microspheres in Virus-Like Particles Purification
Na, Xiangming1,2; Zhou, Weiqing1; Li, Juan1; Su, Zhiguo1; Ma, Guanghui1
2018
Source PublicationPROGRESS IN CHEMISTRY
ISSN1005-281X
Volume30Issue:1Pages:5-13
AbstractPorous polymer microspheres have been widely used in separation and purification of drugs, which are a series of important biochemical engineering products. Formation of porous microspheres is a complex process. Microspheres with pore size below 100 nm is obtained by phase separation of polymers and porogens, while microspheres with pore size above 100 nm can be obtained by phase separation of polymers and water. The porous microspheres with different structures should be delicately designed to meet the application needs. Suspension and seeded polymerizations methods which can be used to fabricate macro-, meso- and nanoporous microspheres are reviewed. Besides, reverse micelles swelling and double emulsion methods are introduced in detail to prepare gigaporous microspheres based on our group 's research. HB-VLPs are used to prove the advantages of gigaporous microspheres in biomacromolecules purification by comparison with mesoporous microspheres.
KeywordPorous Microspheres Gigaporous Microspheres Virus-like Particles (Vlps) Separation And Purification Of Biomacromolecules
SubtypeReview
WOS HeadingsScience & Technology ; Physical Sciences
DOI10.7536/PC170922
Indexed BySCI
Language英语
WOS KeywordMICELLES SWELLING METHOD ; MEDIA
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
Funding OrganizationNational Natural Science Foundation of China(21336010 ; 21476241)
WOS IDWOS:000425931300002
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/24038
Collection生化工程国家重点实验室
Affiliation1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Na, Xiangming,Zhou, Weiqing,Li, Juan,et al. Preparation and Application of Porous Polymer Microspheres in Virus-Like Particles Purification[J]. PROGRESS IN CHEMISTRY,2018,30(1):5-13.
APA Na, Xiangming,Zhou, Weiqing,Li, Juan,Su, Zhiguo,&Ma, Guanghui.(2018).Preparation and Application of Porous Polymer Microspheres in Virus-Like Particles Purification.PROGRESS IN CHEMISTRY,30(1),5-13.
MLA Na, Xiangming,et al."Preparation and Application of Porous Polymer Microspheres in Virus-Like Particles Purification".PROGRESS IN CHEMISTRY 30.1(2018):5-13.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Na, Xiangming]'s Articles
[Zhou, Weiqing]'s Articles
[Li, Juan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Na, Xiangming]'s Articles
[Zhou, Weiqing]'s Articles
[Li, Juan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Na, Xiangming]'s Articles
[Zhou, Weiqing]'s Articles
[Li, Juan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.