Effect of dietary chitosan oligosaccharide supplementation on the pig ovary transcriptome

doi:10.1039/c7ra10172d

CAS OpenIR > 研究所（批量导入）

	Effect of dietary chitosan oligosaccharide supplementation on the pig ovary transcriptome
	Xu, Qingsong 1; Qu, Chen 1; Wan, Jin 2; Cheng, Gong 3,4; Yang, Wen 1; Gong, Changhao 1; He, Jun 2; Du, Yuguang 3
	2018
发表期刊	RSC ADVANCES
ISSN	2046-2069
卷号	8 期号:24 页码:13266-13273
摘要	Fecundity improvement is one of the most important economic traits for the swine industry as it significantly increases production efficiency. Intriguingly, chitosan oligosaccharide (COS), a biomaterial with an active amino group, could promote sow reproductive performance. Therefore, we investigated the effects of dietary COS supplementation on the gene expression differences in the ovaries of sows using the RNA-Seq method. This analysis obtained 13960051 and 14564863 clean reads in control ovary and COS ovary libraries, respectively. A total of 486 differentially expressed genes (DEGs) were thereby identified (FDR 0.001, \|log(2)ratio\| 1). There were 234 up-regulated and 252 down-regulated genes in the COS ovary samples compared with the control ovary samples. A large number of these DEGs were involved in the terms cellular process, cell & cell part and binding. Furthermore, pathway analysis indicated that these DEGs were significantly enriched in 34 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, including cell cycle, progesterone-mediated oocyte maturation, metabolic pathways, oocyte meiosis, and hematopoietic cell lineage among others. These results provided the molecular mechanisms of using COS feed additive for improving sow litter size and prolificacy.
文章类型	Article
WOS标题词	Science & Technology ; Physical Sciences
DOI	10.1039/c7ra10172d
收录类别	SCI
语种	英语
关键词[WOS]	DIFFERENTIALLY EXPRESSED GENES ; RNA-SEQ ; BIOLOGICAL-ACTIVITIES ; PREGNANCY ; REPRODUCTION ; IMPLANTATION ; PERFORMANCE ; NUTRITION ; SURVIVAL ; INSIGHTS
WOS研究方向	Chemistry
WOS类目	Chemistry, Multidisciplinary
项目资助者	Program for Innovative Talents in Higher Education of Liaoning Province ; Dalian high level talent innovation support program(2015R020) ; National Natural Science Foundation of China(31372347)
WOS记录号	WOS:000430018700028
引用统计
文献类型	期刊论文
条目标识符	http://ir.ipe.ac.cn/handle/122111/24132
专题	研究所（批量导入）
作者单位	1.Dalian Ocean Univ, Liaoning Key Lab Marine Anim Immunol & Dis Contro, 52 Heishijiao St, Dalian 116023, Peoples R China 2.Sichuan Agr Univ, Inst Anim Nutr, Chengdu 611130, Sichuan, Peoples R China 3.Chinese Acad Sci, Inst Proc Engn, Beijing 100190, Peoples R China 4.Zhongke Runxin Suzhou Biol Technol Co Ltd, Suzhou 215000, Peoples R China
推荐引用方式 GB/T 7714	Xu, Qingsong,Qu, Chen,Wan, Jin,et al. Effect of dietary chitosan oligosaccharide supplementation on the pig ovary transcriptome[J]. RSC ADVANCES,2018,8(24):13266-13273.
APA	Xu, Qingsong.,Qu, Chen.,Wan, Jin.,Cheng, Gong.,Yang, Wen.,...&Du, Yuguang.(2018).Effect of dietary chitosan oligosaccharide supplementation on the pig ovary transcriptome.RSC ADVANCES,8(24),13266-13273.
MLA	Xu, Qingsong,et al."Effect of dietary chitosan oligosaccharide supplementation on the pig ovary transcriptome".RSC ADVANCES 8.24(2018):13266-13273.