Knowledge Management System Of Institute of process engineering,CAS
| Stability of penicillin G in ionic liquid [Bmim]PF6 | |
| Qi, Jingxian; Liu, Qingfen; Liu, Huizhou | |
| 2018-06-01 | |
| Source Publication | CHINESE JOURNAL OF CHEMICAL ENGINEERING
 |
| ISSN | 1004-9541 |
| Volume | 26Issue:6Pages:1430-1434 |
| Abstract | The extraction of penicillin G by ionic liquid [Bmim] PF6 has exhibited promising prospect. The stability of penicillin G is crucial for developing a green ionic liquid-based extraction technology. In this work, the stability of penicillin G in [Bmim] PF6 was systematically investigated. The results showed the stability of penicillin G was significantly influenced by pH and temperature. It tended to be more stable when pH value increased from 1.5 to 4.0 and the temperature gradually decreased. The half-life (t(1/2)) of penicillin G in [Bmim] PF6 was 17.7 h in the optimal technological condition (pH 2.0 and 10 degrees C), which is enough for the requirement of extraction technology. The reaction of penicillinG in [Bmim] PF6 followed the first order kinetics in the pHrange 2.0-4.0. Three isomers of penicillin G were found through rearrangement at pH 2.0, and their structures were not affected by temperature. (C) 2018 The Chemical Industry and Engineering Society of China, and Chemical Industry Press. All rights reserved. |
| Keyword | Penicillin G Ionic liquids Stability Rearrangement Kinetics |
| DOI | 10.1016/j.cjche.2018.02.030 |
| Language | 英语 |
| WOS Keyword | AQUEOUS 2-PHASE SYSTEM ; WASTE-WATER ; DEGRADATION-PRODUCTS ; RESISTANCE GENES ; RECEIVING RIVER ; EXTRACTION ; TEMPERATURE ; SEPARATION ; SOLVENT ; FATE |
| Funding Project | National Natural Science Foundation of China[21676272] ; Major Science and Technology Project of Water Pollution Control and Management in China[2017ZX07402003] ; Key Research Program of the Chinese Academy of Sciences[ZDRW-ZS-2016-5-3] |
| WOS Research Area | Engineering |
| WOS Subject | Engineering, Chemical |
| Funding Organization | National Natural Science Foundation of China ; Major Science and Technology Project of Water Pollution Control and Management in China ; Key Research Program of the Chinese Academy of Sciences |
| WOS ID | WOS:000440837100022 |
| Publisher | CHEMICAL INDUSTRY PRESS |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/25493 |
| Collection | 中国科学院过程工程研究所 |
| Corresponding Author | Liu, Qingfen; Liu, Huizhou |
| Affiliation | Chinese Acad Sci, Inst Proc Engn, CAS Key Lab Green Proc & Engn, Beijing 100190, Peoples R China |
| Recommended Citation GB/T 7714 | Qi, Jingxian,Liu, Qingfen,Liu, Huizhou. Stability of penicillin G in ionic liquid [Bmim]PF6[J]. CHINESE JOURNAL OF CHEMICAL ENGINEERING,2018,26(6):1430-1434. |
| APA | Qi, Jingxian,Liu, Qingfen,&Liu, Huizhou.(2018).Stability of penicillin G in ionic liquid [Bmim]PF6.CHINESE JOURNAL OF CHEMICAL ENGINEERING,26(6),1430-1434. |
| MLA | Qi, Jingxian,et al."Stability of penicillin G in ionic liquid [Bmim]PF6".CHINESE JOURNAL OF CHEMICAL ENGINEERING 26.6(2018):1430-1434. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment