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Surface functionalization and characterization of magnetic polystyrene microbeads
Alternative TitleLangmuir
Yang, Chengli1; Guan, Yueping1,2; Xing, Jianmin1; Liu, Huizhou1
2008-08-19
Source PublicationLANGMUIR
ISSN0743-7463
Volume24Issue:16Pages:9006-9010
AbstractA new approach to the surface functionalization of magnetic polystyrene microbeads with chloroacetyl chloride in the presence of aluminum chloride was reported. Composite microbeads consisting of polymer-coated iron oxide nanoparticles were prepared by spraying suspension polymerization. Functional chloride groups were introduced onto the sur face of magnetic polystyrene microbeads by surface chemical reaction without destroying the magnetite nanoparticles within the microbeads. First, a complex was synthesized by a reaction between aluminum chloride and chloroacetyl chloride. Then, the complex was added dropwise to the solution of magnetic polystyrene microbeads, and a surface acylation reaction between complex and polystyrene microbeads was carried out. Subsequently, the amino groups were coupled to the magnetic microbeads via an ammonolysis reaction between ethylenediamine and chloride groups on the. acylated magnetic polystyrene microbeads. The chemical composition, surface functional groups, and magnetism of the magnetic polystyrene microbeads before and after surface functionalization were characterized by Fourier transform infrared spectroscopy and vibrating sample magnetometry. The results showed that the surface functionalization reaction had little impact on the magnetism of the microbeads. The content of surface amino groups on the magnetic polystyrene microbeads was found to be 0.2 mmol/g. An affinity dye, Cibacron Blue F3G-A (CB), was then immobilized to prepare a magnetic affinity adsorbent. It was confirmed from X-ray photoelectron spectroscopy spectra that, the CB molecules were covalently coupled on the magnetic microbeads.; A new approach to the surface functionalization of magnetic polystyrene microbeads with chloroacetyl chloride in the presence of aluminum chloride was reported. Composite microbeads consisting of polymer-coated iron oxide nanoparticles were prepared by spraying suspension polymerization. Functional chloride groups were introduced onto the sur face of magnetic polystyrene microbeads by surface chemical reaction without destroying the magnetite nanoparticles within the microbeads. First, a complex was synthesized by a reaction between aluminum chloride and chloroacetyl chloride. Then, the complex was added dropwise to the solution of magnetic polystyrene microbeads, and a surface acylation reaction between complex and polystyrene microbeads was carried out. Subsequently, the amino groups were coupled to the magnetic microbeads via an ammonolysis reaction between ethylenediamine and chloride groups on the. acylated magnetic polystyrene microbeads. The chemical composition, surface functional groups, and magnetism of the magnetic polystyrene microbeads before and after surface functionalization were characterized by Fourier transform infrared spectroscopy and vibrating sample magnetometry. The results showed that the surface functionalization reaction had little impact on the magnetism of the microbeads. The content of surface amino groups on the magnetic polystyrene microbeads was found to be 0.2 mmol/g. An affinity dye, Cibacron Blue F3G-A (CB), was then immobilized to prepare a magnetic affinity adsorbent. It was confirmed from X-ray photoelectron spectroscopy spectra that, the CB molecules were covalently coupled on the magnetic microbeads.
KeywordPoly(Methyl Methacrylate) Protein Adsorption Microspheres Particles Nanoparticles Purification Attachment Separation Beads Acid
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences ; Technology
DOI10.1021/la7040604
URL查看原文
Indexed BySCI
Language英语
WOS KeywordPOLY(METHYL METHACRYLATE) ; PROTEIN ADSORPTION ; MICROSPHERES ; PARTICLES ; NANOPARTICLES ; PURIFICATION ; ATTACHMENT ; SEPARATION ; BEADS ; ACID
WOS Research AreaChemistry ; Materials Science
WOS SubjectChemistry, Multidisciplinary ; Chemistry, Physical ; Materials Science, Multidisciplinary
WOS IDWOS:000258377900093
Citation statistics
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/2891
Collection研究所(批量导入)
Affiliation1.Chinese Acad Sci, Inst Proc Engn, Lab Separat Sci & Engn, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
2.Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Yang, Chengli,Guan, Yueping,Xing, Jianmin,et al. Surface functionalization and characterization of magnetic polystyrene microbeads[J]. LANGMUIR,2008,24(16):9006-9010.
APA Yang, Chengli,Guan, Yueping,Xing, Jianmin,&Liu, Huizhou.(2008).Surface functionalization and characterization of magnetic polystyrene microbeads.LANGMUIR,24(16),9006-9010.
MLA Yang, Chengli,et al."Surface functionalization and characterization of magnetic polystyrene microbeads".LANGMUIR 24.16(2008):9006-9010.
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