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atBioNet- an integrated network analysis tool for genomics and biomarker discovery
Ding, Yijun1; Chen, Minjun2,3; Liu, Zhichao1; Ding, Don1; Ye, Yanbin1; Zhang, Min2,3,4; Kelly, Reagan1; Guo, Li5; Su, Zhenqiang1; Harris, Stephen C.2,3; Qian, Feng1; Ge, Weigong2,3; Fang, Hong1; Xu, Xiaowei2,3,6; Tong, Weida2,3; Fang, H
2012-07-20
Source PublicationBMC GENOMICS
ISSN1471-2164
Volume13Issue:0Pages:文献号: 325
AbstractBackground: Large amounts of mammalian protein-protein interaction (PPI) data have been generated and are available for public use. From a systems biology perspective, Proteins/genes interactions encode the key mechanisms distinguishing disease and health, and such mechanisms can be uncovered through network analysis. An effective network analysis tool should integrate different content-specific PPI databases into a comprehensive network format with a user-friendly platform to identify key functional modules/pathways and the underlying mechanisms of disease and toxicity.
KeywordProtein-protein Interaction Network Analysis Functional Module Disease Biomarker Kegg Pathway Analysis Visualization Tool Genomics
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1186/1471-2164-13-325
Indexed BySCI
Language英语
WOS KeywordSYSTEMIC-LUPUS-ERYTHEMATOSUS ; PROTEIN-INTERACTION NETWORK ; BIOLOGICAL NETWORKS ; BREAST-CANCER ; CHINESE PATIENTS ; EXPRESSION DATA ; GENE ONTOLOGY ; HUMAN-DISEASE ; VISUALIZATION ; MODULES
WOS Research AreaBiotechnology & Applied Microbiology ; Genetics & Heredity
WOS SubjectBiotechnology & Applied Microbiology ; Genetics & Heredity
WOS IDWOS:000308938200001
Citation statistics
Cited Times:19[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/3216
Collection多相复杂系统国家重点实验室
Corresponding AuthorFang, H
Affiliation1.FDAs Natl Ctr Toxicol Res, ICF Int, Jefferson, AR 72079 USA
2.US FDA, Div Bioinformat, Natl Ctr Toxicol Res, Jefferson, AR 72079 USA
3.US FDA, Div Biostat, Natl Ctr Toxicol Res, Jefferson, AR 72079 USA
4.Univ Texas MD Anderson Canc Ctr, Dept Lymphoma & Myeloma, Houston, TX 77054 USA
5.Chinese Acad Sci, Inst Proc Engn, State Key Lab Multiphase Complex Syst, Beijing 100190, Peoples R China
6.Univ Arkansas, Dept Informat Sci, Little Rock, AR 72204 USA
Recommended Citation
GB/T 7714
Ding, Yijun,Chen, Minjun,Liu, Zhichao,et al. atBioNet- an integrated network analysis tool for genomics and biomarker discovery[J]. BMC GENOMICS,2012,13(0):文献号: 325.
APA Ding, Yijun.,Chen, Minjun.,Liu, Zhichao.,Ding, Don.,Ye, Yanbin.,...&Fang, H.(2012).atBioNet- an integrated network analysis tool for genomics and biomarker discovery.BMC GENOMICS,13(0),文献号: 325.
MLA Ding, Yijun,et al."atBioNet- an integrated network analysis tool for genomics and biomarker discovery".BMC GENOMICS 13.0(2012):文献号: 325.
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