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comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen
Wang Tong1; Li Qing1; Zhang Guifeng2; Zhou Gang3; Yu Xin3; Zhang Jing3; Wang Xiumei4; Tang Zhihui1
2016
Source Publicationfrontiersofmaterialsscience
ISSN2095-025X
Volume10Issue:2Pages:122
AbstractBone scaffolds are critical in current implant and periodontal regeneration approaches. In this study, we prepared a novel composite type-l collagen and hydroxyapatite (HA)/β-tricaleium phosphate (TCP) scaffold (CHTS) by incorporating type-1 collagen and bovine calcined bone granules, prepared as a mixture of 50% HA and 50% TCP, by freeze drying. We then characterized the CHTS and determined its cytotoxic effects. Additionally, ridge preservation experiments were carried out to evaluate the clinical effects of the CHTS. The results demonstrated that the composite scaffolds had good surface morphology and no cytotoxicity. Additionally, an in vivo experiment in an animal model showed that the CHTS performed equally as well as Bio-Oss Collagen, a widely used bone graft in ridge preservation. These findings revealed that the CHTS, which contained natural constituents of bone, could be used as a scaffold for bone regeneration and clinical use.
Language英语
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/36016
Collection中国科学院过程工程研究所
Affiliation1.北京大学
2.中国科学院过程工程研究所
3.北京航空航天大学
4.清华大学
Recommended Citation
GB/T 7714
Wang Tong,Li Qing,Zhang Guifeng,et al. comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen[J]. frontiersofmaterialsscience,2016,10(2):122.
APA Wang Tong.,Li Qing.,Zhang Guifeng.,Zhou Gang.,Yu Xin.,...&Tang Zhihui.(2016).comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen.frontiersofmaterialsscience,10(2),122.
MLA Wang Tong,et al."comparativeevaluationofabiomimiccollagenhydroxyapatitetricaleiumphosphatescaffoldinalveolarridgepreservationwithbioosscollagen".frontiersofmaterialsscience 10.2(2016):122.
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