Knowledge Management System Of Institute of process engineering,CAS
| 双亲嵌段共聚物p103对牛血清白蛋白构象的影响 | |
| 王靖; 郭晨; 梁向峰; 郑丽丽; 陈澍; 马俊鹤; 刘会洲 | |
| 2006 | |
| Source Publication | 分析化学
 |
| ISSN | 0253-3820 |
| Volume | 34Issue:12Pages:1711 |
| Abstract | Fourier transform infrared and Fournier transform -Raman spectroscopy were applied to investigate the interaction between Poly( ethylene oxide) -poly( propylene oxide) -poly( ethylene oxide) ( PEO-PPO-PEO) block copolymer (Pluronic P103) and bovine serum albumin (BSA). Microenvironment of some amino acids and the conformation of S-S bond in BSA were influenced by Pluronic P103, when Pluronic P103 was added. Pluronic P103 also could change some alpha-helixes into beta-sheets. The secondary structure of BSA showed little change at lower P103 concentration when the concentration of P103 is not lower than 16 g/L. alpha-helixes decreased from 45. 9% to 40%, and beta-sheets increased from 6. 1% to 17%, in the meantime the random structure showed a little decrease. |
| Language | 英语 |
| Document Type | 期刊论文 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/36777 |
| Collection | 中国科学院过程工程研究所 |
| Affiliation | 中国科学院过程工程研究所 |
| First Author Affilication | 中国科学院过程工程研究所 |
| Recommended Citation GB/T 7714 | 王靖,郭晨,梁向峰,等. 双亲嵌段共聚物p103对牛血清白蛋白构象的影响[J]. 分析化学,2006,34(12):1711. |
| APA | 王靖.,郭晨.,梁向峰.,郑丽丽.,陈澍.,...&刘会洲.(2006).双亲嵌段共聚物p103对牛血清白蛋白构象的影响.分析化学,34(12),1711. |
| MLA | 王靖,et al."双亲嵌段共聚物p103对牛血清白蛋白构象的影响".分析化学 34.12(2006):1711. |
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