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| Hollow mesoporous carbon@Pt Janus nanomotors with dual response of H2O2 and near-infrared light for active cargo delivery | |
| Xing, Yi1; Zhou, Mengyun1; Du, Xin1; Li, Xiaoyu2; Li, Jianqiang2; Xu, Tailin1; Zhang, Xueji1 | |
| 2019-12-01 | |
| Source Publication | APPLIED MATERIALS TODAY
 |
| ISSN | 2352-9407 |
| Volume | 17Pages:85-91 |
| Abstract | Mesoporous carbon nanoparticles (NPs) are widely used to construct nano-theranostic systems due to their excellent physicochemical properties. Herein, we introduce these mesoporous NPs as nanocarriers to build self-propelled transport systems. Such nanocarriers are successfully fabricated by depositing Pt NPs onto the half-sphere surface. Compared with conventional silica-based nanomotors, hollow mesoporous carbon nanospheres (HMCNs) based nanomotors can achieve a high loading efficiency (1370 mg/g) of anticancer drug doxorubicin hydrochloride (DOX) due to its hydrophobic nature. The enhanced motion is observed by introducing the NIR-light irradiation due to the local thermophoresis from the upward temperature of HMCNs and also observed by introducing H2O2 that drives the HMCNs@Pt by the asymmetric decomposition. Interestingly, such enhanced motion also results in the increase of the amount of HMCNs adhering to the surface of living cancer cells, which is beneficial for enhancing the efficiency of drug delivery. This synergetic carbon-based transport system with high cargo loading capacity and dual actuated autonomous motion ability displays immense potential for further functional "smart" devices. (C) 2019 Elsevier Ltd. All rights reserved. |
| Keyword | Hollow mesoporous carbon spheres Pt nanoparticles Janus nanomotors Hybrid propulsion Cargo delivery |
| DOI | 10.1016/j.apmt.2019.07.017 |
| Language | 英语 |
| WOS Keyword | MICRO/NANOMOTORS ; NANOPARTICLES ; MICROSPHERES ; FABRICATION ; PROPULSION ; TRANSPORT ; MOTION ; CORE |
| Funding Project | Fundamental Research Fundsfor the Central Universities[2302015-06500017] ; Fundamental Research Fundsfor the Central Universities[FRF-BR-17-032A] ; Fundamental Research Fundsfor the Central Universities[FRF-BR-17-002B] ; Fundamental Research Fundsfor the Central Universities[FRF-BD-17-016A] ; National Natural Science Foundation of China[51671181] ; National Natural Science Foundation of China[21804007] ; National Natural Science Foundation of China[21501009] ; Beijing Municipal Science and Technology Commission[z131102002813058] |
| WOS Research Area | Materials Science |
| WOS Subject | Materials Science, Multidisciplinary |
| Funding Organization | Fundamental Research Fundsfor the Central Universities ; National Natural Science Foundation of China ; Beijing Municipal Science and Technology Commission |
| WOS ID | WOS:000502851600004 |
| Publisher | ELSEVIER |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/38673 |
| Collection | 中国科学院过程工程研究所 |
| Corresponding Author | Du, Xin |
| Affiliation | 1.Univ Sci & Technol Beijing, Beijing Key Lab Bioengn & Sensing Technol, Dept Chem & Biol Engn, Res Ctr Bioengn & Sensing Technol, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Key Lab Green Proc & Engn, Inst Proc Engn, Natl Engn Lab Hydromet Cleaner Prod Technol, Beijing 100190, Peoples R China |
| Recommended Citation GB/T 7714 | Xing, Yi,Zhou, Mengyun,Du, Xin,et al. Hollow mesoporous carbon@Pt Janus nanomotors with dual response of H2O2 and near-infrared light for active cargo delivery[J]. APPLIED MATERIALS TODAY,2019,17:85-91. |
| APA | Xing, Yi.,Zhou, Mengyun.,Du, Xin.,Li, Xiaoyu.,Li, Jianqiang.,...&Zhang, Xueji.(2019).Hollow mesoporous carbon@Pt Janus nanomotors with dual response of H2O2 and near-infrared light for active cargo delivery.APPLIED MATERIALS TODAY,17,85-91. |
| MLA | Xing, Yi,et al."Hollow mesoporous carbon@Pt Janus nanomotors with dual response of H2O2 and near-infrared light for active cargo delivery".APPLIED MATERIALS TODAY 17(2019):85-91. |
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