CAS OpenIR
Nano-Fragrance with pH-Sensitive Release Property for Improvement of Central Nervous System
Wang, Xiangyu1,2; Lu, Zhiguo2,3; Shen, Jie2,3; Niu, Yunwei4,6; Xiao, Zuobing4,6; Chen, Lei5; Hao, Jifu1; Zhang, Xin2
2020-02-01
Source PublicationJOURNAL OF BIOMEDICAL NANOTECHNOLOGY
ISSN1550-7033
Volume16Issue:2Pages:193-200
AbstractFragrance has the function of nerve regulation and is widely used in aromatic therapy. However, the rapid release of fragrance can cause discomfort in the body and have side effects. Besides, fragrance is still released when not in use, which can reduce the service life of fragrance products and limit their application. Herein, cationic nanoparticles loaded with linalool were prepared and then adhered on the silk. The fragrance-encapsulated nanoparticles have pH-sensitive release property. Linalool was promoted to release in acidic condition and was suppressed to release in alkaline condition. In addition, the nano-fragrance with controlled release properties had regulatory effects on the central nervous system. It had the effect of relieving stress according to the open field tests. Besides, it increased the expression levels of dopamine, acetylcholine and GABA according to results of liquid chromatograph-mass spectrometer. Therefore, these cationic nano-fragrance with pH-sensitive release property have the potential for aromatherapy.
KeywordAromatic Therapy Nano-Fragrance pH-Sensitive Release Property Silk Improvement of Central Nervous System
DOI10.1166/jbn.2020.2873
Language英语
WOS KeywordDRUG-DELIVERY ; MICELLES ; DISEASE ; NANOTUBES ; LIPOSOMES ; LINKAGES ; ANXIETY ; ABILITY
Funding ProjectNational High Technology Research and Development Program[2016YFA0200303] ; Beijing Natural Science Foundation[L172046] ; Beijing Natural Science Foundation[2192057] ; National Natural Science Foundation of China[31771095] ; National Natural Science Foundation of China[21875254] ; National Natural Science Foundation of China[51573188] ; Beijing Municipal Science and Technology Commission[Z161100002616015]
WOS Research AreaScience & Technology - Other Topics ; Materials Science
WOS SubjectNanoscience & Nanotechnology ; Materials Science, Biomaterials
Funding OrganizationNational High Technology Research and Development Program ; Beijing Natural Science Foundation ; National Natural Science Foundation of China ; Beijing Municipal Science and Technology Commission
WOS IDWOS:000524973800005
PublisherAMER SCIENTIFIC PUBLISHERS
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/40010
Collection中国科学院过程工程研究所
Corresponding AuthorChen, Lei; Hao, Jifu; Zhang, Xin
Affiliation1.Shandong First Med Univ & Shandong Acad Med Sci, Sch Pharmaceut Sci, Tai An 271016, Shandong, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China
4.Shanghai Res Inst Fragrance & Flavor Ind, Shanghai 200232, Peoples R China
5.Chinese PLA Peoples Liberat Army Gen Hosp, Med Ctr 6, Dept Obstet & Gynecol, Beijing 100048, Peoples R China
6.Shanghai Inst Technol, Sch Perfume & Aroma Technol, Shanghai 200233, Peoples R China
Recommended Citation
GB/T 7714
Wang, Xiangyu,Lu, Zhiguo,Shen, Jie,et al. Nano-Fragrance with pH-Sensitive Release Property for Improvement of Central Nervous System[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2020,16(2):193-200.
APA Wang, Xiangyu.,Lu, Zhiguo.,Shen, Jie.,Niu, Yunwei.,Xiao, Zuobing.,...&Zhang, Xin.(2020).Nano-Fragrance with pH-Sensitive Release Property for Improvement of Central Nervous System.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,16(2),193-200.
MLA Wang, Xiangyu,et al."Nano-Fragrance with pH-Sensitive Release Property for Improvement of Central Nervous System".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 16.2(2020):193-200.
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