3D Bio-Printing Fabrication and Properties of Graphene Dispersion-based Hybrid Scaffolds
Peng,Jun1,2; Li,Liying1,2; Nie,Yi2,3; Liu,Tianqing1; Song,Kedong1
Source PublicationJournal of Physics: Conference Series

Abstract Peripheral nerve is an important tissue of human body, which is distributed in various parts of human body, and has the function of connecting central nervous system and other organs. The self-repair ability of the nervous system is poor. However, 3D bio-printed neural tissue-engineered scaffolds offer a promising solution. In this study, graphene (Gr) was dispersed by a certain method, and then blended with gelatin (Gel) and sodium alginate (SA) to prepare a mixed bio-ink. Performance of different ratios of bio-ink was evaluated to determine the best printing ratio of the material. Four groups of Gr/Gel/SA scaffolds (The concentrations of graphene were 0%, 0.02%, 0.08% and 0.2% (w/v%), respectively) were prepared by using 3D printing technology. The mechanical strength, contact angle, degradation rate and water absorption of bio-scaffolds were compared to select the most suitable scaffold to support cell proliferation and differentiation, PC12 cells were used to study the biocompatibility of the scaffolds. This article aims to get the most optimized scaffolds.

WOS IDIOP:1742-6588-1622-1-012062
PublisherIOP Publishing
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Document Type期刊论文
Affiliation1.State Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China
2.Zhengzhou Institute of Emerging Industrial Technology, Zhengzhou 450000, China
3.Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
Recommended Citation
GB/T 7714
Peng,Jun,Li,Liying,Nie,Yi,et al. 3D Bio-Printing Fabrication and Properties of Graphene Dispersion-based Hybrid Scaffolds[J]. Journal of Physics: Conference Series,2020,1622(1).
APA Peng,Jun,Li,Liying,Nie,Yi,Liu,Tianqing,&Song,Kedong.(2020).3D Bio-Printing Fabrication and Properties of Graphene Dispersion-based Hybrid Scaffolds.Journal of Physics: Conference Series,1622(1).
MLA Peng,Jun,et al."3D Bio-Printing Fabrication and Properties of Graphene Dispersion-based Hybrid Scaffolds".Journal of Physics: Conference Series 1622.1(2020).
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