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| Hollow Mesoporous Silica Nanoparticles Loaded with Eugenol for Regulating the Central Nervous System | |
| Wang, Jianze1,2; Lu, Zhiguo2,3; Shen, Jie2,3; Peng, Huan2,3; Zhang, Tianlu2,3; Niu, Yunwei4,5; Xiao, Zuobing4,5; Hao, Jifu1; Zhang, Xin2 | |
| 2020-05-01 | |
| Source Publication | JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
 |
| ISSN | 1550-7033 |
| Volume | 16Issue:5Pages:652-658 |
| Abstract | Fragrances are extensively applied in food, daily chemicals, tobacco and medicine industries. However, too strong volatility of fragrances results in a fast release rate, thereby reducing the usage time of aromatherapy products. Although loading fragrances into nanomaterials is capable of slowing their rates of release, the encapsulation efficiency of traditional nanomaterials is very low, and the nanomaterials themselves are not stable. Herein, hollow mesoporous silica nanoparticles (hMSNs) were designed for encapsulation of eugenol and he nano-fragrance was named EG@hMSNs. The structure of IP: 127.0.0.1 On: Sat, 19 Sep 2020 06:40:19 hMSNs was stable and the encapsulatin rate of eugnol reached 46.5%. Beids, EG@hMSNs could significantly slow Copyright: American Scientific P blishers the release rate of eugenol. Subsequently, the EG@hMSNs were testified that they had positive roles in stress relief by Delivered by Ingenta open field tests. The molecular mechanisms of these positive effects on the central nervous system were then explored. Furthermore, the preparation method of hMSCs was simple, and the preparation cost was low. Therefore, EG@hMSNs are expected to be industrially produced and have a great application prospect. |
| Keyword | Hollow Mesoporous Silica Nanoparticles Eugenol Slow Release Stress Relief Anti-Anxiety |
| DOI | 10.1166/jbn.2020.2919 |
| Language | 英语 |
| WOS Keyword | DRUG-DELIVERY ; BREAST-CANCER ; FRAGRANCE ; MICELLES ; CURCUMIN ; RELEASE ; ANXIETY ; CHEMISTRY ; LIPOSOMES ; CARRIERS |
| Funding Project | National High Technology Research and Development Program[2016YFA0200303] ; Beijing Natural Science Foundation[L172046,2192057] ; National Natural Science Foundation of China[31771095] ; National Natural Science Foundation of China[21875254] ; National Natural Science Foundation of China[51573188] |
| WOS Research Area | Science & Technology - Other Topics ; Materials Science |
| WOS Subject | Nanoscience & Nanotechnology ; Materials Science, Biomaterials |
| Funding Organization | National High Technology Research and Development Program ; Beijing Natural Science Foundation ; National Natural Science Foundation of China |
| WOS ID | WOS:000573055400001 |
| Publisher | AMER SCIENTIFIC PUBLISHERS |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/42240 |
| Collection | 中国科学院过程工程研究所 |
| Corresponding Author | Hao, Jifu; Zhang, Xin |
| Affiliation | 1.Shandong First Med Univ & Shandong Acad Med Sci, Sch Pharmaceut Sci, Tai An 271016, Shandong, Peoples R China 2.Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China 4.Shanghai Res Inst Fragrance & Flavor Ind, Shanghai 200232, Peoples R China 5.Shanghai Inst Technol, Sch Perfume & Aroma Technol, Shanghai 200233, Peoples R China |
| Recommended Citation GB/T 7714 | Wang, Jianze,Lu, Zhiguo,Shen, Jie,et al. Hollow Mesoporous Silica Nanoparticles Loaded with Eugenol for Regulating the Central Nervous System[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2020,16(5):652-658. |
| APA | Wang, Jianze.,Lu, Zhiguo.,Shen, Jie.,Peng, Huan.,Zhang, Tianlu.,...&Zhang, Xin.(2020).Hollow Mesoporous Silica Nanoparticles Loaded with Eugenol for Regulating the Central Nervous System.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,16(5),652-658. |
| MLA | Wang, Jianze,et al."Hollow Mesoporous Silica Nanoparticles Loaded with Eugenol for Regulating the Central Nervous System".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 16.5(2020):652-658. |
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