Knowledge Management System Of Institute of process engineering,CAS
| Cyclic dipeptides: Biological activities and self-assembled materials | |
| Zhao, Kaili1,2; Xing, Ruirui1,2; Yan, Xuehai1,2 | |
| 2020-10-10 | |
| Source Publication | PEPTIDE SCIENCE
 |
| ISSN | 2475-8817 |
| Pages | 13 |
| Abstract | Cyclic dipeptides (CDPs) are the smallest cyclic peptides containing 2,5-diketopiperazine rings. CDPs have advantages of structures and properties, including excellent hydrogen-bonding-forming ability (two hydrogen bonding acceptors and two hydrogen bonding donors), structural rigidity, and enzymatic stability, which make CDPs potential candidates as core scaffolds for drug discovery and building blocks for self-assembly. In this review, we focus on distinctive bioactivities of CDPs, such as antitumor, antimicrobial, antivirus and antioxidant, and self-assembly properties of CDPs and their derivatives. Emphasis will be placed on the thermodynamics and kinetics CDPs self-assembly and applications of self-assembled materials. This review provides insight into the development of CDPs and their corresponding assembled materials as drug delivery carriers and optoelectronic materials. |
| Keyword | antibacterial antitumor diketopiperazine optical waveguiding self-assembly |
| DOI | 10.1002/pep2.24202 |
| Language | 英语 |
| WOS Keyword | RHABDITID ENTOMOPATHOGENIC NEMATODE ; SOLID-PHASE ; ASPERGILLUS-FUMIGATUS ; MEDICINAL CHEMISTRY ; IN-VITRO ; DIKETOPIPERAZINES ; PEPTIDE ; 2,5-DIKETOPIPERAZINES ; TRYPROSTATINS ; BACTERIA |
| Funding Project | National Natural Science Foundation of China[21802144] ; Key Research Program of Frontier Sciences of Chinese Academy of Sciences[QYZDB-SSW-JSC034] ; Innovation Research Community Science Fund[21821005] ; National Natural Science Fund BRICS STI Framework Program[51861145304] |
| WOS Research Area | Biochemistry & Molecular Biology ; Biophysics |
| WOS Subject | Biochemistry & Molecular Biology ; Biophysics |
| Funding Organization | National Natural Science Foundation of China ; Key Research Program of Frontier Sciences of Chinese Academy of Sciences ; Innovation Research Community Science Fund ; National Natural Science Fund BRICS STI Framework Program |
| WOS ID | WOS:000579329300001 |
| Publisher | WILEY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/42424 |
| Collection | 中国科学院过程工程研究所 |
| Corresponding Author | Xing, Ruirui; Yan, Xuehai |
| Affiliation | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Sch Chem Engn, Beijing, Peoples R China |
| First Author Affilication | Center of lonic Liquids and Green Engineering |
| Corresponding Author Affilication | Center of lonic Liquids and Green Engineering |
| Recommended Citation GB/T 7714 | Zhao, Kaili,Xing, Ruirui,Yan, Xuehai. Cyclic dipeptides: Biological activities and self-assembled materials[J]. PEPTIDE SCIENCE,2020:13. |
| APA | Zhao, Kaili,Xing, Ruirui,&Yan, Xuehai.(2020).Cyclic dipeptides: Biological activities and self-assembled materials.PEPTIDE SCIENCE,13. |
| MLA | Zhao, Kaili,et al."Cyclic dipeptides: Biological activities and self-assembled materials".PEPTIDE SCIENCE (2020):13. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment