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| Antimonene Nanosheets-Based Z-Scheme Heterostructure with Enhanced Reactive Oxygen Species Generation and Photothermal Conversion Efficiency for Photonic Therapy of Cancer | |
| Kang, Yong1,2; Li, Zhengjun1; Yang, Yanli1; Su, Zhiguo1; Ji, Xiaoyuan3; Zhang, Songping1 | |
| 2020-11-16 | |
| Source Publication | ADVANCED HEALTHCARE MATERIALS
 |
| ISSN | 2192-2640 |
| Pages | 12 |
| Abstract | A Z-scheme heterojunction with high separation efficiency of photogenerated electrons and holes and enhanced reduction/oxidation potentials, which can enhance reactive oxygen species generation and photothermal conversion efficiency, exhibits tremendous potential in photonic theranostics. Herein, antimonene nanosheets (Sb NSs) are functionalized with photosensitizer 5,10,15,20-Tetrakis(4-hydroxy-phenyl)-21H,12H-porphine (THPP) and a poly(ethylene glycol) (PEG) modifier. The Sb-THPP-PEG NSs thus fabricated are found to form a Z-scheme heterojunction structure between Sb and THPP, based on their valence band and bandgap level analysis. The Z-scheme heterojunction structure enables the Sb-THPP-PEG NSs multiple promising features for cancer therapy. Firstly, due to improved electron-hole pairs separation efficiency and redox potential, new reactive oxygen species center dot O-2(-) is generated, besides the production of O-1(2) by THPP. Secondly, the assembly of THPP enhances the NIR-light-to-heat conversion of Sb NS, a photothermal conversion efficiency as high as 44.6% is obtained by this Sb-THPP-PEG NSs photonic nanomedicine. Moreover, the photothermal, fluorescent, and photoacoustic imaging properties of Sb-THPP-PEG NSs allow multimodal imaging-guided tumor treatment. |
| Keyword | antimonene nanomedicine photodynamic therapy photothermal therapy Z‐ scheme heterojunction |
| DOI | 10.1002/adhm.202001835 |
| Language | 英语 |
| WOS Keyword | PHOTODYNAMIC THERAPY ; DELIVERY ; NANOPARTICLES ; NANOPLATFORM ; NANORODS ; AGENT ; DRUG |
| Funding Project | National Natural Science Foundation of China[21676276] |
| WOS Research Area | Engineering ; Science & Technology - Other Topics ; Materials Science |
| WOS Subject | Engineering, Biomedical ; Nanoscience & Nanotechnology ; Materials Science, Biomaterials |
| Funding Organization | National Natural Science Foundation of China |
| WOS ID | WOS:000589659700001 |
| Publisher | WILEY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/42561 |
| Collection | 中国科学院过程工程研究所 |
| Corresponding Author | Ji, Xiaoyuan; Zhang, Songping |
| Affiliation | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Sch Chem Engn, 19 Yuquan Rd, Beijing 100049, Peoples R China 3.Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Guangzhou 510275, Peoples R China |
| Recommended Citation GB/T 7714 | Kang, Yong,Li, Zhengjun,Yang, Yanli,et al. Antimonene Nanosheets-Based Z-Scheme Heterostructure with Enhanced Reactive Oxygen Species Generation and Photothermal Conversion Efficiency for Photonic Therapy of Cancer[J]. ADVANCED HEALTHCARE MATERIALS,2020:12. |
| APA | Kang, Yong,Li, Zhengjun,Yang, Yanli,Su, Zhiguo,Ji, Xiaoyuan,&Zhang, Songping.(2020).Antimonene Nanosheets-Based Z-Scheme Heterostructure with Enhanced Reactive Oxygen Species Generation and Photothermal Conversion Efficiency for Photonic Therapy of Cancer.ADVANCED HEALTHCARE MATERIALS,12. |
| MLA | Kang, Yong,et al."Antimonene Nanosheets-Based Z-Scheme Heterostructure with Enhanced Reactive Oxygen Species Generation and Photothermal Conversion Efficiency for Photonic Therapy of Cancer".ADVANCED HEALTHCARE MATERIALS (2020):12. |
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