Advances of Nanoparticles for Leukemia Treatment
Shen, Jie1,2; Lu, Zhiguo1,2; Wang, Jianze1; Zhang, Tianlu1; Yang, Jun1; Li, Yan1; Liu, Guiying3; Zhang, Xin1

Leukemia is a liquid tumor caused by a hematopoietic stem cell malignant clone, which seriously affects the normal function of the hematopoietic system. Conventional drugs have poor therapeutic effects due to their poor specificity and stability. With the development of nanotechnology, nonviral nanoparticles bring hope for the efficient treatment of leukemia. Nanoparticles are easily modified. They can be designed to target lesion sites and control drug release. Thereby, nanoparticles can improve the effects of drugs and reduce side effects. This review mainly focuses on and summarizes the current research progress of nanoparticles to deliver different leukemia therapeutic drugs, as to demonstrate the potential of nanoparticles in leukemia treatment.

KeywordLeukemia Nanoparticles Delivery Drugs Microenvironment
WOS KeywordAcute Myeloid-leukemia ; Bone-marrow Microenvironment ; Hematopoietic Stem-cells ; In-vivo ; Drug-delivery ; Gemtuzumab Ozogamicin ; Photodynamic Therapy ; Crispr-cas9 System ; Gold Nanoparticles ; Alzheimers-disease
Funding ProjectNational High Technology Research and Development Program[2016YFA0200303] ; Beijing Natural Science Foundation[L172046,2192057] ; National Natural Science Foundation of China[31771095] ; National Natural Science Foundation of China[21875254] ; National Natural Science Foundation of China[51573188]
WOS Research AreaMaterials Science
WOS SubjectMaterials Science, bioMaterials
Funding OrganizationNational High Technology Research and Development Program ; Beijing Natural Science Foundation ; National Natural Science Foundation of China
WOS IDWOS:000599989300002
Citation statistics
Document Type期刊论文
Corresponding AuthorLiu, Guiying; Zhang, Xin
Affiliation1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China
3.Capital Med Univ, Dept Pediat, Affiliated Beijing Anzhen Hosp, Beijing 100029, Peoples R China
Recommended Citation
GB/T 7714
Shen, Jie,Lu, Zhiguo,Wang, Jianze,et al. Advances of Nanoparticles for Leukemia Treatment[J]. ACS BIOMATERIALS SCIENCE & ENGINEERING,2020,6(12):6478-6489.
APA Shen, Jie.,Lu, Zhiguo.,Wang, Jianze.,Zhang, Tianlu.,Yang, Jun.,...&Zhang, Xin.(2020).Advances of Nanoparticles for Leukemia Treatment.ACS BIOMATERIALS SCIENCE & ENGINEERING,6(12),6478-6489.
MLA Shen, Jie,et al."Advances of Nanoparticles for Leukemia Treatment".ACS BIOMATERIALS SCIENCE & ENGINEERING 6.12(2020):6478-6489.
Files in This Item:
File Name/Size DocType Version Access License
Advances of Nanopart(7419KB)期刊论文出版稿限制开放CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Shen, Jie]'s Articles
[Lu, Zhiguo]'s Articles
[Wang, Jianze]'s Articles
Baidu academic
Similar articles in Baidu academic
[Shen, Jie]'s Articles
[Lu, Zhiguo]'s Articles
[Wang, Jianze]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Shen, Jie]'s Articles
[Lu, Zhiguo]'s Articles
[Wang, Jianze]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.