Advances of Nanoparticles for Leukemia Treatment

doi:10.1021/acsbiomaterials.0c01040

CAS OpenIR

	Advances of Nanoparticles for Leukemia Treatment
	Shen, Jie 1,2; Lu, Zhiguo 1,2; Wang, Jianze 1; Zhang, Tianlu 1; Yang, Jun 1; Li, Yan 1; Liu, Guiying 3; Zhang, Xin 1
	2020-12-01
Source Publication	ACS BIOMATERIALS SCIENCE & ENGINEERING
ISSN	2373-9878
Volume	6 Issue:12 Pages:6478-6489
Abstract	Leukemia is a liquid tumor caused by a hematopoietic stem cell malignant clone, which seriously affects the normal function of the hematopoietic system. Conventional drugs have poor therapeutic effects due to their poor specificity and stability. With the development of nanotechnology, nonviral nanoparticles bring hope for the efficient treatment of leukemia. Nanoparticles are easily modified. They can be designed to target lesion sites and control drug release. Thereby, nanoparticles can improve the effects of drugs and reduce side effects. This review mainly focuses on and summarizes the current research progress of nanoparticles to deliver different leukemia therapeutic drugs, as to demonstrate the potential of nanoparticles in leukemia treatment.
Keyword	Leukemia Nanoparticles Delivery Drugs Microenvironment
DOI	10.1021/acsbiomaterials.0c01040
Language	英语
WOS Keyword	Acute Myeloid-leukemia ; Bone-marrow Microenvironment ; Hematopoietic Stem-cells ; In-vivo ; Drug-delivery ; Gemtuzumab Ozogamicin ; Photodynamic Therapy ; Crispr-cas9 System ; Gold Nanoparticles ; Alzheimers-disease
Funding Project	National High Technology Research and Development Program[2016YFA0200303] ; Beijing Natural Science Foundation[L172046,2192057] ; National Natural Science Foundation of China[31771095] ; National Natural Science Foundation of China[21875254] ; National Natural Science Foundation of China[51573188]
WOS Research Area	Materials Science
WOS Subject	Materials Science, bioMaterials
Funding Organization	National High Technology Research and Development Program ; Beijing Natural Science Foundation ; National Natural Science Foundation of China
WOS ID	WOS:000599989300002
Publisher	AMER CHEMICAL SOC
Citation statistics
Document Type	期刊论文
Identifier	http://ir.ipe.ac.cn/handle/122111/42960
Collection	中国科学院过程工程研究所
Corresponding Author	Liu, Guiying; Zhang, Xin
Affiliation	1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China 3.Capital Med Univ, Dept Pediat, Affiliated Beijing Anzhen Hosp, Beijing 100029, Peoples R China
Recommended Citation GB/T 7714	Shen, Jie,Lu, Zhiguo,Wang, Jianze,et al. Advances of Nanoparticles for Leukemia Treatment[J]. ACS BIOMATERIALS SCIENCE & ENGINEERING,2020,6(12):6478-6489.
APA	Shen, Jie.,Lu, Zhiguo.,Wang, Jianze.,Zhang, Tianlu.,Yang, Jun.,...&Zhang, Xin.(2020).Advances of Nanoparticles for Leukemia Treatment.ACS BIOMATERIALS SCIENCE & ENGINEERING,6(12),6478-6489.
MLA	Shen, Jie,et al."Advances of Nanoparticles for Leukemia Treatment".ACS BIOMATERIALS SCIENCE & ENGINEERING 6.12(2020):6478-6489.

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