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| Principles of regulating particle multiscale structures for controlling particle-cell interaction process | |
| Song, Cui1,2; Zhang, Xiao1; Wei, Wei1,2; Ma, Guanghui1,2 | |
| 2021-03-15 | |
| Source Publication | CHEMICAL ENGINEERING SCIENCE
 |
| ISSN | 0009-2509 |
| Volume | 232Pages:19 |
| Abstract | Particles make extensively physical contact with cells after entering the body, which mediate a series of particle-cell interaction processes. These interaction processes induce different physiological responses of cells and indicate the potential biomedical applications of particles. Hence, controlling the particlecell interaction processes have been attracting more and more attentions. Among factors that affect particle-cell interaction processes, regulating particle multiscale structures is the most dominant. To date, numerous principles have been developed, including integrating particles with different physicochemical properties such as size, shape, elasticity and surface chemistry by various preparation technologies, coating particle surface with cell membrane to endow its biomimetic properties, taking advantage of the particle's dimensional effect, etc. In this review, we will highlight recent progresses on these princi ples, and corresponding biomedical applications in drug delivery, immune modulation and tissue engineering. The challenges and perspectives of regulating particle multiscale structures for controlling interaction processes will also be discussed. (C) 2020 Elsevier Ltd. All rights reserved. |
| Keyword | Particles Multiscale structures Particle-cell interactions Biomedical applications |
| DOI | 10.1016/j.ces.2020.116343 |
| Language | 英语 |
| WOS Keyword | RECEPTOR-MEDIATED ENDOCYTOSIS ; DRUG-DELIVERY SYSTEMS ; COATED GOLD NANOPARTICLES ; MESOPOROUS SILICA ; IMMUNE-RESPONSE ; GRAPHENE OXIDE ; IN-VITRO ; INTRACELLULAR TRAFFICKING ; TUMOR MICROENVIRONMENT ; MEMBRANE PENETRATION |
| Funding Project | Innovative Research Group Project of the National Natural Science Foundation of China[21821005] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB29040303] |
| WOS Research Area | Engineering |
| WOS Subject | Engineering, Chemical |
| Funding Organization | Innovative Research Group Project of the National Natural Science Foundation of China ; Strategic Priority Research Program of the Chinese Academy of Sciences |
| WOS ID | WOS:000608126300009 |
| Publisher | PERGAMON-ELSEVIER SCIENCE LTD |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/43225 |
| Collection | 中国科学院过程工程研究所 |
| Corresponding Author | Wei, Wei; Ma, Guanghui |
| Affiliation | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Song, Cui,Zhang, Xiao,Wei, Wei,et al. Principles of regulating particle multiscale structures for controlling particle-cell interaction process[J]. CHEMICAL ENGINEERING SCIENCE,2021,232:19. |
| APA | Song, Cui,Zhang, Xiao,Wei, Wei,&Ma, Guanghui.(2021).Principles of regulating particle multiscale structures for controlling particle-cell interaction process.CHEMICAL ENGINEERING SCIENCE,232,19. |
| MLA | Song, Cui,et al."Principles of regulating particle multiscale structures for controlling particle-cell interaction process".CHEMICAL ENGINEERING SCIENCE 232(2021):19. |
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