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Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production
Li, Xianhui1,2,3; Su, Ziran2; Chen, Xueming4; Luo, Jianquan5; Pinelo, Manuel2
2021-04-01
Source PublicationJOURNAL OF MEMBRANE SCIENCE
ISSN0376-7388
Volume623Pages:12
AbstractProducing oligodextran with an enzymatic membrane reactor (EMR) is a promising alternative to traditional fermentation processes due to its high efficiency and environmental compatibility. Process analysis and optimization of an EMR system used for producing oligodextran are critical to improving EMR operating stability and cost effectiveness. We herein developed a mathematical model to evaluate the effects of operating conditions and membrane properties on the reaction-separation behavior of an EMR. Our analysis shows that tailoring a membrane with large porosity and uniform pore size distribution can simultaneously improve the product quality and production efficiency. The optimal parameters of operating pressure and agitation speed for achieving high production efficiency depend on the selection of operating mode. EMR prefers higher operating pressure to increase the production efficiency under water feeding mode. However, since the membrane suffered severer fouling under substrate feeding mode, the extensive agitation is required to inhibit membrane fouling and enhance production yield. Our work paves a new avenue towards the fundamental understanding and designing of highly effective and low consumptive EMR for oligodextran production.
KeywordMathematical model Enzymatic membrane reactor Oligodextran Process optimization Membrane fouling
DOI10.1016/j.memsci.2021.119082
Language英语
Funding ProjectEuropean Union[713683] ; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)[GML2019ZD0403] ; Program for Guangdong Introducing Innovative and Entrepreneurial Teams[2019ZT08L213]
WOS Research AreaEngineering ; Polymer Science
WOS SubjectEngineering, Chemical ; Polymer Science
Funding OrganizationEuropean Union ; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) ; Program for Guangdong Introducing Innovative and Entrepreneurial Teams
WOS IDWOS:000619230200001
PublisherELSEVIER
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/43587
Collection中国科学院过程工程研究所
Corresponding AuthorLuo, Jianquan; Pinelo, Manuel
Affiliation1.Guangdong Univ Technol, Inst Environm & Ecol Engn, Minist Educ, Key Lab City Cluster Environm Safety & Green Dev, Guangzhou 510006, Peoples R China
2.Tech Univ Denmark, Dept Chem & Biochem Engn, Proc & Syst Engn Ctr, DK-2800 Lyngby, Denmark
3.Southern Marine Sci & Engn Guangdong Lab Guangzho, Guangzhou 511458, Peoples R China
4.Fuzhou Univ, Coll Environm & Resources, Fuzhou 350116, Fujian, Peoples R China
5.Chinese Acad Sci, Univ Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Li, Xianhui,Su, Ziran,Chen, Xueming,et al. Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production[J]. JOURNAL OF MEMBRANE SCIENCE,2021,623:12.
APA Li, Xianhui,Su, Ziran,Chen, Xueming,Luo, Jianquan,&Pinelo, Manuel.(2021).Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production.JOURNAL OF MEMBRANE SCIENCE,623,12.
MLA Li, Xianhui,et al."Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production".JOURNAL OF MEMBRANE SCIENCE 623(2021):12.
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