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Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production | |
Li, Xianhui1,2,3; Su, Ziran2; Chen, Xueming4; Luo, Jianquan5; Pinelo, Manuel2 | |
2021-04-01 | |
Source Publication | JOURNAL OF MEMBRANE SCIENCE
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ISSN | 0376-7388 |
Volume | 623Pages:12 |
Abstract | Producing oligodextran with an enzymatic membrane reactor (EMR) is a promising alternative to traditional fermentation processes due to its high efficiency and environmental compatibility. Process analysis and optimization of an EMR system used for producing oligodextran are critical to improving EMR operating stability and cost effectiveness. We herein developed a mathematical model to evaluate the effects of operating conditions and membrane properties on the reaction-separation behavior of an EMR. Our analysis shows that tailoring a membrane with large porosity and uniform pore size distribution can simultaneously improve the product quality and production efficiency. The optimal parameters of operating pressure and agitation speed for achieving high production efficiency depend on the selection of operating mode. EMR prefers higher operating pressure to increase the production efficiency under water feeding mode. However, since the membrane suffered severer fouling under substrate feeding mode, the extensive agitation is required to inhibit membrane fouling and enhance production yield. Our work paves a new avenue towards the fundamental understanding and designing of highly effective and low consumptive EMR for oligodextran production. |
Keyword | Mathematical model Enzymatic membrane reactor Oligodextran Process optimization Membrane fouling |
DOI | 10.1016/j.memsci.2021.119082 |
Language | 英语 |
Funding Project | European Union[713683] ; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)[GML2019ZD0403] ; Program for Guangdong Introducing Innovative and Entrepreneurial Teams[2019ZT08L213] |
WOS Research Area | Engineering ; Polymer Science |
WOS Subject | Engineering, Chemical ; Polymer Science |
Funding Organization | European Union ; Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) ; Program for Guangdong Introducing Innovative and Entrepreneurial Teams |
WOS ID | WOS:000619230200001 |
Publisher | ELSEVIER |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ipe.ac.cn/handle/122111/43587 |
Collection | 中国科学院过程工程研究所 |
Corresponding Author | Luo, Jianquan; Pinelo, Manuel |
Affiliation | 1.Guangdong Univ Technol, Inst Environm & Ecol Engn, Minist Educ, Key Lab City Cluster Environm Safety & Green Dev, Guangzhou 510006, Peoples R China 2.Tech Univ Denmark, Dept Chem & Biochem Engn, Proc & Syst Engn Ctr, DK-2800 Lyngby, Denmark 3.Southern Marine Sci & Engn Guangdong Lab Guangzho, Guangzhou 511458, Peoples R China 4.Fuzhou Univ, Coll Environm & Resources, Fuzhou 350116, Fujian, Peoples R China 5.Chinese Acad Sci, Univ Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China |
Recommended Citation GB/T 7714 | Li, Xianhui,Su, Ziran,Chen, Xueming,et al. Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production[J]. JOURNAL OF MEMBRANE SCIENCE,2021,623:12. |
APA | Li, Xianhui,Su, Ziran,Chen, Xueming,Luo, Jianquan,&Pinelo, Manuel.(2021).Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production.JOURNAL OF MEMBRANE SCIENCE,623,12. |
MLA | Li, Xianhui,et al."Mathematical modelling of reaction-separation in an enzymatic membrane reactor during oligodextran production".JOURNAL OF MEMBRANE SCIENCE 623(2021):12. |
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