CAS OpenIR
3D Printing for Biological Scaffolds using Poly(Ionic Liquid)/Gelatin/Sodium Alginate Ink
Zhang, Manman1,2; Li, Liying3; Wang, Meiju4; Li, Tao1; Song, Kedong3; Nie, Yi2,5; Ren, Baozeng1
2021-05-02
Source PublicationMACROMOLECULAR MATERIALS AND ENGINEERING
ISSN1438-7492
Pages11
Abstract

The poly(ionic liquid)s (PILs) have attracted a wide range of applications in thermo-responsive materials, carbon materials, catalysis, porous polymers, separation and absorption materials, and biological field due to their favorable tunability and biological functions. However, the applications of PILs in bio-scaffold are rarely studied. In the present work, the ionic liquid (IL) monomer (1-vinyl-3-butylimidazolium chloride, [VBIM]Cl) is cross-linked with other three compounds, respectively, to synthesize three kinds of PILs (PIL1, PIL2, and PIL3). Furthermore, individually cross-linked PILs are added into gelatin (Gel)/sodium alginate (SA) solution aiming to prepare biological inks (bio-inks) for 3D printing. The water absorption, degradation rate, and porosity of the bio-scaffolds are measured to evaluate the physicochemical characteristics, while the PC12 cell line is used to evaluate the biocompatibility of the bio-scaffolds through cell proliferation. These results demonstrate that the biological activity of the bio-scaffold can be varied at the tendency of PIL1 < PIL3 < PIL2, providing a potential prospect for the application of PILs in tissue-engineered bio-scaffolds.

Keyword3d Printing Bio‐ Scaffolds Poly(Ionic Liquid)
DOI10.1002/mame.202100084
Language英语
Funding ProjectNational Natural Science Foundation of China[21776276] ; Zhengzhou High Level Talent[20180300045]
WOS Research AreaMaterials Science ; Polymer Science
WOS SubjectMaterials Science, Multidisciplinary ; Polymer Science
Funding OrganizationNational Natural Science Foundation of China ; Zhengzhou High Level Talent
WOS IDWOS:000646087300001
PublisherWILEY-V C H VERLAG GMBH
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ipe.ac.cn/handle/122111/48521
Collection中国科学院过程工程研究所
Corresponding AuthorNie, Yi; Ren, Baozeng
Affiliation1.Zhengzhou Univ, Sch Chem Engn, Zhengzhou 450000, Peoples R China
2.Zhengzhou Inst Emerging Ind Technol, Zhengzhou 450000, Peoples R China
3.Dalian Univ Technol, Dalian R&D Ctr Stem Cell & Tissue Engn, State Key Lab Fine Chem, Dalian 116024, Peoples R China
4.Yantai Marine Environm Monitoring Cent Stn North, Yantai 264006, Peoples R China
5.Chinese Acad Sci, Inst Proc Engn, Key Lab Green Proc & Engn, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Manman,Li, Liying,Wang, Meiju,et al. 3D Printing for Biological Scaffolds using Poly(Ionic Liquid)/Gelatin/Sodium Alginate Ink[J]. MACROMOLECULAR MATERIALS AND ENGINEERING,2021:11.
APA Zhang, Manman.,Li, Liying.,Wang, Meiju.,Li, Tao.,Song, Kedong.,...&Ren, Baozeng.(2021).3D Printing for Biological Scaffolds using Poly(Ionic Liquid)/Gelatin/Sodium Alginate Ink.MACROMOLECULAR MATERIALS AND ENGINEERING,11.
MLA Zhang, Manman,et al."3D Printing for Biological Scaffolds using Poly(Ionic Liquid)/Gelatin/Sodium Alginate Ink".MACROMOLECULAR MATERIALS AND ENGINEERING (2021):11.
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