Knowledge Management System Of Institute of process engineering,CAS
| Ionozyme: ionic liquids as solvent and stabilizer for efficient bioactivation of CO2 | |
| Ji, Xiuling1; Xue, Yaju1; Li, Zhuang1; Liu, Yanrong4; Liu, Lei1; Busk, Peter Kamp5; Lange, Lene6; Huang, Yuhong1,2,3; Zhang, Suojiang1,2 | |
| 2021-08-18 | |
| Source Publication | GREEN CHEMISTRY
 |
| ISSN | 1463-9262 |
| Pages | 11 |
| Abstract | The efficient bioactivation of CO2 provides an alternative new strategy for producing high value chemicals and fuels. Normally, in vitro activation of CO2 can be achieved by using formate dehydrogenase (FDH). However, the CO2 solubility and the activity of commercial FDHCb remain a tough challenge for the efficient bioactivation of CO2. Here, we report a new "ionozyme" strategy created by using ionic liquids (ILs) as a solvent and enzyme stabilizer, resulting in a 142.3-fold increase in CO2 conversion over FDHCb. The ionozyme (FDHPa-[CH][Pro]-[TMGH][PhO]) was first developed by combing a discovered novel FDHPa with an efficient synergistic ionic microenvironment. The remarkable performance of this ionozyme is attributed to forming key intermediates [CH][ProCOO] and [TMGH][PhOCOO], stabilizing the enzyme structure with increased solvation structure, and shortening the distance (3.9 angstrom) between NADH and CO2 to favor the hydride transfer by facilitating their relative orientation and forming new hydrogen bonds at the active sites. This bioactivation of CO2 by this specific ionozyme represents ideal starting points for the sustainable carbon cycle. |
| DOI | 10.1039/d1gc02503a |
| Language | 英语 |
| WOS Keyword | MULTI-ENZYMATIC CONVERSION ; FORMATE DEHYDROGENASE ; CARBON-DIOXIDE ; REDUCTION ; SYSTEM ; GREEN ; RESOLUTION ; MECHANISM ; METHANOL ; ENZYMES |
| Funding Project | Dalian National Laboratory for Clean Energy (DNL) Cooperation Fund, CAS[DNL201909] ; Natural Science Foundation of Beijing[2204097] ; Innovation Academy for Green Manufacture, CAS[IAGM2020C19] ; CAS Pioneer Hundred Program |
| WOS Research Area | Chemistry ; Science & Technology - Other Topics |
| WOS Subject | Chemistry, Multidisciplinary ; Green & Sustainable Science & Technology |
| Funding Organization | Dalian National Laboratory for Clean Energy (DNL) Cooperation Fund, CAS ; Natural Science Foundation of Beijing ; Innovation Academy for Green Manufacture, CAS ; CAS Pioneer Hundred Program |
| WOS ID | WOS:000687280400001 |
| Publisher | ROYAL SOC CHEMISTRY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/49920 |
| Collection | 中国科学院过程工程研究所 |
| Corresponding Author | Huang, Yuhong; Zhang, Suojiang |
| Affiliation | 1.Chinese Acad Sci, Inst Proc Engn, Beijing Key Lab Ion Liquids Clean Proc, CAS Key Lab Green Proc & Engn,State Key Lab Multi, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Innovat Acad Green Manufacture, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China 4.Lulea Univ Technol, Div Energy Sci, Energy Engn, Lulea, Sweden 5.Roskilde Univ, Dept Sci & Environm, Univ Vej 1, DK-4000 Roskilde, Denmark 6.Bioecon Res & Advisory, DK-2500 Copenhagen, Valby, Denmark |
| Recommended Citation GB/T 7714 | Ji, Xiuling,Xue, Yaju,Li, Zhuang,et al. Ionozyme: ionic liquids as solvent and stabilizer for efficient bioactivation of CO2[J]. GREEN CHEMISTRY,2021:11. |
| APA | Ji, Xiuling.,Xue, Yaju.,Li, Zhuang.,Liu, Yanrong.,Liu, Lei.,...&Zhang, Suojiang.(2021).Ionozyme: ionic liquids as solvent and stabilizer for efficient bioactivation of CO2.GREEN CHEMISTRY,11. |
| MLA | Ji, Xiuling,et al."Ionozyme: ionic liquids as solvent and stabilizer for efficient bioactivation of CO2".GREEN CHEMISTRY (2021):11. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment