Preparation and Properties of Decellularized Sheep Kidney Derived Matrix Scaffolds
Zheng,Le1; Zheng,Shuangshuang3; Chen,Zilong1; Li,Xiangqin1; Liu,Chunyan4; Bai,Jie5; Jiang,Daqing5; Nie,Yi3,6; Zhang,Jingying2; Liu,Tianqing1; Song,Kedong1
Source PublicationJournal of Physics: Conference Series
AbstractAbstract Scaffolds from tissues or organs have nanoscale microstructures. Derived matrix scaffolds prepared by decellularized method can provide more cell attachment sites, which is conducive to cell adhesion, proliferation, differentiation and other physiological activities on scaffolds. In this study, the sheep kidney decellularized matrix scaffold was prepared by the method of decellularization. Due to the poor mechanical properties of the decellularized matrix, the cross linking method was adopted to enhance its mechanical properties. The decellularization efficiency of sheep renal matrix scaffolds was observed by scanning electron microscopy and histological staining, and the biocompatibility of the scaffolds was investigated by inoculating adipose derived stem cells. It was found that the scaffold had good decellularization effect and good pore structure.
WOS IDIOP:JPCS_2160_1_012014
PublisherIOP Publishing
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Document Type期刊论文
Affiliation1.State Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian 116024, China
2.The Second Clinical Medical College, Guangdong Medical University, Dongguan, 523808, Guangdong, China
3.Zhengzhou Institute of Emerging Industrial Technology, Zhengzhou 450000, China
4.Department of Nephrology, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116000, P.R. China
5.Department of Breast Surgery, Cancer Hospital of China Medical University, Shenyang 110042, China
6.Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
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GB/T 7714
Zheng,Le,Zheng,Shuangshuang,Chen,Zilong,et al. Preparation and Properties of Decellularized Sheep Kidney Derived Matrix Scaffolds[J]. Journal of Physics: Conference Series,2022,2160(1).
APA Zheng,Le.,Zheng,Shuangshuang.,Chen,Zilong.,Li,Xiangqin.,Liu,Chunyan.,...&Song,Kedong.(2022).Preparation and Properties of Decellularized Sheep Kidney Derived Matrix Scaffolds.Journal of Physics: Conference Series,2160(1).
MLA Zheng,Le,et al."Preparation and Properties of Decellularized Sheep Kidney Derived Matrix Scaffolds".Journal of Physics: Conference Series 2160.1(2022).
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