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DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila
Murali, Thilakam1; Pacifico, Svetlana1; Yu, Jingkai2; Guest, Stephen1; Roberts, George G., III1; Finley, Russell L., Jr.1,3; Finley, RL
2011
Source PublicationNUCLEIC ACIDS RESEARCH
ISSN0305-1048
Volume39Issue:增刊 1Pages:D736-D743
AbstractDroID (http://droidb.org/), the Drosophila Interactions Database, is a comprehensive public resource for Drosophila gene and protein interactions. DroID contains genetic interactions and experimentally detected protein-protein interactions curated from the literature and from external databases, and predicted protein interactions based on experiments in other species. Protein interactions are annotated with experimental details and periodically updated confidence scores. Data in DroID is accessible through user-friendly, intuitive interfaces that allow simple or advanced searches and graphical visualization of interaction networks. DroID has been expanded to include interaction types that enable more complete analyses of the genetic networks that underlie biological processes. In addition to protein-protein and genetic interactions, the database now includes transcription factor-gene and regulatory RNA-gene interactions. In addition, DroID now has more gene expression data that can be used to search and filter interaction networks. Orthologous gene mappings of Drosophila genes to other organisms are also available to facilitate finding interactions based on gene names and identifiers for a number of common model organisms and humans. Improvements have been made to the web and graphical interfaces to help biologists gain a comprehensive view of the interaction networks relevant to the genes and systems that they study.
KeywordFunctional Genomic Data Interaction Database Regulatory Networks Interaction Map Micrornas Targets Tools Information Expression Flybase
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1093/nar/gkq1092
Indexed BySCI
Language英语
WOS KeywordFUNCTIONAL GENOMIC DATA ; INTERACTION DATABASE ; REGULATORY NETWORKS ; INTERACTION MAP ; MICRORNAS ; TARGETS ; TOOLS ; INFORMATION ; EXPRESSION ; FLYBASE
WOS Research AreaBiochemistry & Molecular Biology
WOS SubjectBiochemistry & Molecular Biology
WOS IDWOS:000285831700117
Citation statistics
Cited Times:114[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/5402
Collection生化工程国家重点实验室
Corresponding AuthorFinley, RL
Affiliation1.Wayne State Univ, Sch Med, Ctr Mol Med & Genet, Detroit, MI 48202 USA
2.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing, Peoples R China
3.Wayne State Univ, Sch Med, Dept Biochem & Mol Biol, Detroit, MI USA
Recommended Citation
GB/T 7714
Murali, Thilakam,Pacifico, Svetlana,Yu, Jingkai,et al. DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila[J]. NUCLEIC ACIDS RESEARCH,2011,39(增刊 1):D736-D743.
APA Murali, Thilakam.,Pacifico, Svetlana.,Yu, Jingkai.,Guest, Stephen.,Roberts, George G., III.,...&Finley, RL.(2011).DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila.NUCLEIC ACIDS RESEARCH,39(增刊 1),D736-D743.
MLA Murali, Thilakam,et al."DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila".NUCLEIC ACIDS RESEARCH 39.增刊 1(2011):D736-D743.
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