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Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method
Liu, Binbin1,2; Yang, Maohua1,2; Qi, Benkun1,2; Chen, Xiangrong1; Su, Zhiguo1; Wan, Yinhua1; Wan, YH
2010-11-15
Source PublicationBIOCHEMICAL ENGINEERING JOURNAL
ISSN1369-703X
Volume52Issue:2-3Pages:212-219
AbstractThe effects of five alternative nitrogen sources namely malt sprout (MS) corn steep liquor (CSL) NH(4)Cl NH(4)NO(3) and diamine citrate (DC) were investigated on the L-(+)-lactic acid (LA) production by thermophile Lactobacillus plantarum As 1 3 Through the statistical analysis of the results by three steps of response surface methodology (RSM) design MS and CSL were found to have significant effects on the LA production and their optimal concentrations in the medium should be 16 0 g/L and 12 0 g/L respectively The verification of the optimized medium showed that the maximum specific growth rate (mu(m)) was 1 09 h(-1) the cell yield coefficient (Y(X/S)) and the L-(+)-lactic acid yield coefficient (Y(P/S)) were 0 233 (OD(620)/g) and 0 98 (g/g) and the maximum volumetric productivity and the average volumetric productivity were 13 0 g/L h and 3 20 g/L h respectively The results indicate that the LA production can also be enhanced with the inexpensive nitrogen source alternatives (C) 2010 Elsevier B V All rights reserved
KeywordL-(+)-lactic Acid Thermophile Lactobacillus Plantarum As 1 3 Malt Sprout Corn Steep Liquor Response Surface Methodology Nitrogen Source
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Technology
DOI10.1016/j.bej.2010.08.013
Indexed BySCI
Language英语
WOS KeywordSTEEPEST ASCENT METHOD ; L(+) LACTIC-ACID ; CASEI NRRL B-441 ; MEMBRANE BIOREACTOR ; FACTORIAL DESIGN ; UNSTRUCTURED MODEL ; WHEY PERMEATE ; CHEESE WHEY ; OPTIMIZATION ; FERMENTATION
WOS Research AreaBiotechnology & Applied Microbiology ; Engineering
WOS SubjectBiotechnology & Applied Microbiology ; Engineering, Chemical
WOS IDWOS:000284571200015
Citation statistics
Cited Times:37[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/5571
Collection生化工程国家重点实验室
Corresponding AuthorWan, YH
Affiliation1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Liu, Binbin,Yang, Maohua,Qi, Benkun,et al. Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method[J]. BIOCHEMICAL ENGINEERING JOURNAL,2010,52(2-3):212-219.
APA Liu, Binbin.,Yang, Maohua.,Qi, Benkun.,Chen, Xiangrong.,Su, Zhiguo.,...&Wan, YH.(2010).Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method.BIOCHEMICAL ENGINEERING JOURNAL,52(2-3),212-219.
MLA Liu, Binbin,et al."Optimizing L-(+)-lactic acid production by thermophile Lactobacillus plantarum As 1 3 using alternative nitrogen sources with response surface method".BIOCHEMICAL ENGINEERING JOURNAL 52.2-3(2010):212-219.
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