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Critical influence of osmotic pressure on continuous production of glycerol by an osmophilic strain of Candida krusei in a multistage cascade bioreactor
Alternative TitleProcess Biochem.
Liu, YQ; Liu, DH; Su, Q; Liu, JR; Xie, DM
2002-11-01
Source PublicationPROCESS BIOCHEMISTRY
ISSN1359-5113
Volume38Issue:3Pages:427-432
AbstractThe effects of osmotic pressure and dilution rate were investigated on the continuous production of glycerol in a multistage cascade bioreactor. The results showed that high osmotic pressure could improve fermentation performance significantly. At a dilution rate of 0.050 h(-1) and feeding 400 g l(-1) glucose solution, a glycerol yield of 25.0% based on glucose consumed and a maximum productivity of 19.4 g l(-1) per day were obtained, respectively, in a six-stage cascade bioreactor. When the dilution rate was increased from 0.023 to 0.085 h(-1) the glycerol yield, based on biomass, remained constant, but specific productivity increased by 94.7%. Productivity increased by only 46.6% due to low biomass concentration in the bioreactor at the higher dilution rates. (C) 2002 Elsevier Science Ltd. All rights reserved.; The effects of osmotic pressure and dilution rate were investigated on the continuous production of glycerol in a multistage cascade bioreactor. The results showed that high osmotic pressure could improve fermentation performance significantly. At a dilution rate of 0.050 h(-1) and feeding 400 g l(-1) glucose solution, a glycerol yield of 25.0% based on glucose consumed and a maximum productivity of 19.4 g l(-1) per day were obtained, respectively, in a six-stage cascade bioreactor. When the dilution rate was increased from 0.023 to 0.085 h(-1) the glycerol yield, based on biomass, remained constant, but specific productivity increased by 94.7%. Productivity increased by only 46.6% due to low biomass concentration in the bioreactor at the higher dilution rates. (C) 2002 Elsevier Science Ltd. All rights reserved.
KeywordMultistage Cascade Bioreactor Osmophilic Yeast Osmotic Pressure Dilution Rate Glycerol
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Technology
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Indexed BySCI
Language英语
WOS KeywordYEAST SACCHAROMYCES-CEREVISIAE ; PICHIA-FARINOSA ; SALT-TOLERANCE
WOS Research AreaBiochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Engineering
WOS SubjectBiochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Engineering, Chemical
WOS IDWOS:000179665400019
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Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/5625
Collection研究所(批量导入)
Affiliation1.Tsing Hua Univ, Dept Chem Engn, Beijing 100084, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
3.NW Minor Univ, Dept Chem, Lanzhou 730030, Gansu, Peoples R China
Recommended Citation
GB/T 7714
Liu, YQ,Liu, DH,Su, Q,et al. Critical influence of osmotic pressure on continuous production of glycerol by an osmophilic strain of Candida krusei in a multistage cascade bioreactor[J]. PROCESS BIOCHEMISTRY,2002,38(3):427-432.
APA Liu, YQ,Liu, DH,Su, Q,Liu, JR,&Xie, DM.(2002).Critical influence of osmotic pressure on continuous production of glycerol by an osmophilic strain of Candida krusei in a multistage cascade bioreactor.PROCESS BIOCHEMISTRY,38(3),427-432.
MLA Liu, YQ,et al."Critical influence of osmotic pressure on continuous production of glycerol by an osmophilic strain of Candida krusei in a multistage cascade bioreactor".PROCESS BIOCHEMISTRY 38.3(2002):427-432.
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