Knowledge Management System Of Institute of process engineering,CAS
| A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells | |
| Alternative Title | Biotechnol. Lett. |
| Lu, XJ; Cong, W; Ouyang, F | |
| 2002-05-01 | |
| Source Publication | BIOTECHNOLOGY LETTERS
 |
| ISSN | 0141-5492 |
| Volume | 24Issue:10Pages:825-830 |
| Abstract | A cone disk atomizer has been designed for preparation of gelatin/polystyrene magnetic microcapsules for use as microcarriers in anchorage-dependent mammalian cell culture. This apparatus facilitates continuous production of microcapsules and ignores surfactants or organic solvents in traditional emulsion. Compared with the flat-disk atomizer, the feeding flow is subjected to a normal pressure provided by the special cone-shaped disk and liquid slide is dramatically decreased in the cone-disk atomizer. A flow-rate-limitation is observed in both flat-disk atomization and cone-disk atomization. A 36% increase in flow-rate limitation was observed in cone-disk atomization than in flat-disk atomization indicating the potential of this method for large-scale preparations.; A cone disk atomizer has been designed for preparation of gelatin/polystyrene magnetic microcapsules for use as microcarriers in anchorage-dependent mammalian cell culture. This apparatus facilitates continuous production of microcapsules and ignores surfactants or organic solvents in traditional emulsion. Compared with the flat-disk atomizer, the feeding flow is subjected to a normal pressure provided by the special cone-shaped disk and liquid slide is dramatically decreased in the cone-disk atomizer. A flow-rate-limitation is observed in both flat-disk atomization and cone-disk atomization. A 36% increase in flow-rate limitation was observed in cone-disk atomization than in flat-disk atomization indicating the potential of this method for large-scale preparations. |
| Keyword | Atomization Cone-disk Large-scale Magnetic Beads Microcapsules |
| Subtype | Article |
| WOS Headings | Science & Technology ; Life Sciences & Biomedicine |
| URL | 查看原文 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Biotechnology & Applied Microbiology |
| WOS Subject | Biotechnology & Applied Microbiology |
| WOS ID | WOS:000175634500014 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Version | 出版稿 |
| Identifier | http://ir.ipe.ac.cn/handle/122111/5630 |
| Collection | 研究所（批量导入） |
| Affiliation | Chinese Acad Sci, Inst Proc Engn, Natl Lab Biochem Engn, Beijing 100080, Peoples R China |
| Recommended Citation GB/T 7714 | Lu, XJ,Cong, W,Ouyang, F. A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells[J]. BIOTECHNOLOGY LETTERS,2002,24(10):825-830. |
| APA | Lu, XJ,Cong, W,&Ouyang, F.(2002).A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells.BIOTECHNOLOGY LETTERS,24(10),825-830. |
| MLA | Lu, XJ,et al."A cone disk atomizer for production of biocompatible magnetic microcapsules for culture of anchorage-dependent mammalian cells".BIOTECHNOLOGY LETTERS 24.10(2002):825-830. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| A cone disk atomizer（102KB） | 限制开放 | CC BY-NC-SA | Application Full Text | |||
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