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Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes
Alternative TitleSep. Sci. Technol.
Zhang, JD; Cai, ZL; Cong, W; Su, ZG; Fan, PY
2002
Source PublicationSEPARATION SCIENCE AND TECHNOLOGY
ISSN0149-6395
Volume37Issue:13Pages:3039-3051
AbstractAdsorption and deposition of proteins in/on membranes were two main mechanisms of protein fouling in microfiltration. To distinguish the two mechanisms, adsorption and deposition were studied under both static and filtration conditions. The results demonstrated that under static conditions, adsorption had an equilibrium and the equilibrium amount of adsorption was almost constant even in solutions with different concentrations. The maximum adsorption occurred at isoelectric point pH value, and the amount of protein absorbed was similar to that of monolayer type adsorption. In actual microfiltration, adsorption and deposition of proteins occur simultaneously and the adsorption has an equilibrium with adsorption values similar to that of static adsorption. The amount of protein that deposited onto the membranes was simply proportional to filtration volume of the solution. The result can be described by a mathematical model.; Adsorption and deposition of proteins in/on membranes were two main mechanisms of protein fouling in microfiltration. To distinguish the two mechanisms, adsorption and deposition were studied under both static and filtration conditions. The results demonstrated that under static conditions, adsorption had an equilibrium and the equilibrium amount of adsorption was almost constant even in solutions with different concentrations. The maximum adsorption occurred at isoelectric point pH value, and the amount of protein absorbed was similar to that of monolayer type adsorption. In actual microfiltration, adsorption and deposition of proteins occur simultaneously and the adsorption has an equilibrium with adsorption values similar to that of static adsorption. The amount of protein that deposited onto the membranes was simply proportional to filtration volume of the solution. The result can be described by a mathematical model.
KeywordMicrofiltration Protein Fouling Adsorption Deposition
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences ; Technology
URL查看原文
Indexed BySCI
Language英语
WOS KeywordINTERMOLECULAR FORCES ; FILTRATION ; FLUX ; ULTRAFILTRATION ; RELEVANCE
WOS Research AreaChemistry ; Engineering
WOS SubjectChemistry, Multidisciplinary ; Engineering, Chemical
WOS IDWOS:000178523600005
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/5680
Collection研究所(批量导入)
AffiliationChinese Acad Sci, Inst Proc Engn, Natl Lab Biochem Engn China, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Zhang, JD,Cai, ZL,Cong, W,et al. Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes[J]. SEPARATION SCIENCE AND TECHNOLOGY,2002,37(13):3039-3051.
APA Zhang, JD,Cai, ZL,Cong, W,Su, ZG,&Fan, PY.(2002).Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes.SEPARATION SCIENCE AND TECHNOLOGY,37(13),3039-3051.
MLA Zhang, JD,et al."Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes".SEPARATION SCIENCE AND TECHNOLOGY 37.13(2002):3039-3051.
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