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Lipase-catalyzed hydrolysis of methyl-3-phenylglycidate
Alternative TitleChin. Chem. Lett.
Zheng, GJ; Wang, JJ; Ren, TR; Yang, L; Sun, WR
2001-04-01
Source PublicationCHINESE CHEMICAL LETTERS
ISSN1001-8417
Volume12Issue:4Pages:305-306
AbstractThe enzymatic resolution of racemic methyl 3-phenylgycidate was investigated. It was found that the hydrolysis rate of (2S, 3R)-enantiomer was faster than that of (2R. 3S)-enantiomer by a new lipase. At optimal condition 96% of (2R. 3S)-methyl phenylglycidate with ee of 100% was recovered from the racemic mixture.; The enzymatic resolution of racemic methyl 3-phenylgycidate was investigated. It was found that the hydrolysis rate of (2S, 3R)-enantiomer was faster than that of (2R. 3S)-enantiomer by a new lipase. At optimal condition 96% of (2R. 3S)-methyl phenylglycidate with ee of 100% was recovered from the racemic mixture.
KeywordLipase Methyl 3-phenylglycidate Resolution Chirality
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
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Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000168213100007
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Version出版稿
Identifierhttp://ir.ipe.ac.cn/handle/122111/5759
Collection研究所(批量导入)
Affiliation1.Chinese Acad Sci, Inst Microbiol, State Key Lab Microbial Resources, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Inst Chem Met, Lab Chem Comp, Beijing 100080, Peoples R China
Recommended Citation
GB/T 7714
Zheng, GJ,Wang, JJ,Ren, TR,et al. Lipase-catalyzed hydrolysis of methyl-3-phenylglycidate[J]. CHINESE CHEMICAL LETTERS,2001,12(4):305-306.
APA Zheng, GJ,Wang, JJ,Ren, TR,Yang, L,&Sun, WR.(2001).Lipase-catalyzed hydrolysis of methyl-3-phenylglycidate.CHINESE CHEMICAL LETTERS,12(4),305-306.
MLA Zheng, GJ,et al."Lipase-catalyzed hydrolysis of methyl-3-phenylglycidate".CHINESE CHEMICAL LETTERS 12.4(2001):305-306.
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